Quantitative measurement of absolute cell volume and intracellular integral refractive index (RI) with dual-wavelength digital holographic microscopy (DHM)

D Boss, J Kühn, C Depeursinge… - … Solutions for Better …, 2012 - spiedigitallibrary.org
Quantitative Phase Imaging techniques including DHM have been applied recently in the
field of cell imaging to monitor and quantify non-invasively dynamic cellular processes …

Cell refractive index for cell biology and disease diagnosis: past, present and future

PY Liu, LK Chin, W Ser, HF Chen, CM Hsieh, CH Lee… - Lab on a Chip, 2016 - pubs.rsc.org
Cell refractive index is a key biophysical parameter, which has been extensively studied. It is
correlated with other cell biophysical properties including mechanical, electrical and optical …

Mapping optical path length and image enhancement using quantitative orientation-independent differential interference contrast microscopy

M Shribak, KG Larkin, D Biggs - Journal of Biomedical Optics, 2017 - spiedigitallibrary.org
We describe the principles of using orientation-independent differential interference contrast
(OI-DIC) microscopy for mapping optical path length (OPL). Computation of the scalar two …

Quantitative interferometric microscopy cytometer based on regularized optical flow algorithm

L Xue, J Vargas, S Wang, Z Li, F Liu - Optics Communications, 2015 - Elsevier
Cell detections and analysis are important in various fields, such as medical observations
and disease diagnoses. In order to analyze the cell parameters as well as observe the …

Single-shot quantitative dispersion phase microscopy

N Lue, JW Kang, TR Hillman, RR Dasari… - Applied physics …, 2012 - pubs.aip.org
We present an imaging modality capable of providing high-speed optical dispersion
measurements of live cells. The technique permits wide-field measurement of the optical …

Is the nuclear refractive index lower than cytoplasm? Validation of phase measurements and implications for light scattering technologies

ZA Steelman, WJ Eldridge, JB Weintraub… - Journal of …, 2017 - Wiley Online Library
The refractive index (RI) of biological materials is a fundamental parameter for the optical
characterization of living systems. Numerous light scattering technologies are grounded in a …

Off-axis interferometric phase microscopy with tripled imaging area

I Frenklach, P Girshovitz, NT Shaked - Optics Letters, 2014 - opg.optica.org
We present an interferometric approach, referred to as interferometry with tripled-imaging
area (ITIA), for tripling the quantitative information that can be collected in a single camera …

Dynamic quantitative phase imaging for biological objects using a pixelated phase mask

K Creath, G Goldstein - Biomedical optics express, 2012 - opg.optica.org
This paper describes research in developing a dynamic quantitative phase imaging
microscope providing instantaneous measurements of dynamic motions within and among …

Confocal simultaneous phase-shifting interferometry

C Zhao, J Tan, J Tang, T Liu, J Liu - Applied Optics, 2011 - opg.optica.org
In order to implement the ultraprecise measurement with large range and long working
distance in confocal microscopy, confocal simultaneous phase-shifting interferometry (C …

Single-shot refractive index slice imaging using spectrally multiplexed optical transfer function reshaping

C Lee, H Hugonnet, J Park, MJ Lee, W Park… - Optics …, 2023 - opg.optica.org
The refractive index (RI) of cells and tissues is crucial in pathophysiology as a noninvasive
and quantitative imaging contrast. Although its measurements have been demonstrated …