Differentiation refers to how closely the neoplastic cells resemble their nonneoplastic
counterparts in the tissue from which they arose. Well-differentiated cancer cells closely …

Neuroendocrine neoplasms arise throughout the body. They are recognized pathologically
based on characteristic morphologic patterns and immunoexpression of neuroendocrine …

Much recent debate has focused on the optimal classification of epithelial neuroendocrine
tumors (NETs). Multiple different systems of terminology, grading, and staging have been …

Neuroendocrine tumours often present a diagnostic and therapeutic challenge. They can
arise almost anywhere in the body, and are therefore associated with a broad range of local …

Epithelial neuroendocrine tumors (NETs) have been the subject of much debate regarding
their optimal classification. Although multiple systems of nomenclature, grading, and staging …

Background: Neuroendocrine differentiation of tumors is often difficult to establish. In the
same manner, the evaluation of the prognostic role of neuroendocrine differentiation may …

Neuroendocrine tumors (NETs) arise in most organs of the body and share many common
pathologic features. However, a variety of different organ-specific systems have been …

Neuroendocrine tumors comprise a family of neoplasms with a wide range of morphologic,
functional, and behavioral characteristics. Their diagnosis depends on the recognition of …

Neuroendocrine neoplasia is described in almost every tissue, either in the pure endocrine
organs, the nerve structures or in the so-called diffuse neuroendocrine system. The current …

Neuroendocrine neoplasms (NEN) develop in many organs, and although they share some
pathological and clinical features, significant differences do exist among different tumor …