CYTOKINES are soluble peptide messengers that are synthesized by lymphocytes (thus,
they were originally called lymphokines), neutrophils, macrophages, and neuronal cells. The …

Ageing is accompanied by 2–4-fold increases in plasma/serum levels of inflammatory
mediators such as cytokines and acute phase proteins. A wide range of factors seems to …

Background How inflammation relates to intrinsic capacity (IC), the composite of physical
and mental capacities, remains undefined. Our study aimed to investigate the cross …

The original definition of sarcopenia refers to the age‐related loss of muscle mass. The
literature suggests that the prevalence of sarcopenia in 60‐to 70‐year‐olds is in the range of …

Sarcopenia, defined as a syndrome rather than as a pathology, is the loss of muscle mass
and function associated with age. Sarcopenia is an enigma for medicine, and despite the …

Physical frailty (PF) and sarcopenia are major health issues in geriatric populations, given
their high prevalence and association with several adverse outcomes. Nevertheless, the …

Background. There is growing evidence for the significant involvement of inflammatory
processes in the development of muscle wasting in old age. Therefore, any disease …

The term sarcopenia refers to the loss of muscle mass that occurs with aging. Sarcopenia is
defined by the European Working Group on Sarcopenia in Older People (EWGSOP) as low …

Sarcopenia is a major component of the frailty syndrome, both being considered as strong
predictors of morbidity, disability, and death in older people. In this review, we explore the …

Ageing is accompanied by chronic inflammatory responses due to elevated circulatory
inflammatory cytokine production. Several inflammatory cytokines have been shown to be …