Cytokines for evaluation of chronic inflammatory status in ageing research: reliability and phenotypic characterisation
L Koelman, O Pivovarova-Ramich, AFH Pfeiffer… - Immunity & …, 2019 - Springer
Background There is a growing interest in the role of inflammageing for chronic disease
development. Cytokines are potent soluble immune mediators that can be used as target …
development. Cytokines are potent soluble immune mediators that can be used as target …
Inflammation and frailty measures in older people
RE Hubbard, MS O'Mahony, GM Savva… - Journal of cellular …, 2009 - Wiley Online Library
Inflammation in patients defined as frail by Fried's phenotypic definition may be related to
sarcopenia. This study aimed to investigate inflammation in older patients across different …
sarcopenia. This study aimed to investigate inflammation in older patients across different …
Inflammatory response in the elderly
RF Grimble - Current Opinion in Clinical Nutrition & Metabolic …, 2003 - journals.lww.com
Ageing is associated with increased levels of chronic inflammation. This plays a major role
in the decline in immune function and lean body mass. Anti-inflammatory nutrient therapy …
in the decline in immune function and lean body mass. Anti-inflammatory nutrient therapy …
Aging of the endocrine system and its potential impact on sarcopenia
Sarcopenia, occurring as a primary consequence of aging, is a progressive generalized
decline of skeletal muscle mass, strength and function. The pathophysiology of sarcopenia …
decline of skeletal muscle mass, strength and function. The pathophysiology of sarcopenia …
Aging is associated with circulating cytokine dysregulation
L Álvarez-Rodríguez, M López-Hoyos… - Cellular …, 2012 - Elsevier
PURPOSE: Aging is accompanied by a progressive increase in pro-inflammatory cytokine
status. However, little is known about the development of age-dependent modifications in …
status. However, little is known about the development of age-dependent modifications in …
Sarcopenia, a neurogenic syndrome?
P Kwan - Journal of aging research, 2013 - Wiley Online Library
Sarcopenia is an aging‐associated condition, which is currently characterized by the loss of
muscle mass and muscle strength. However, there is no consensus regarding its …
muscle mass and muscle strength. However, there is no consensus regarding its …
Inflammaging: age and systemic, cellular, and nuclear inflammatory biology in older adults
Systemic inflammation is associated with increasing age. Yet, there are limited data about
the association between age and systemic inflammation within older adults, and whether …
the association between age and systemic inflammation within older adults, and whether …
[HTML][HTML] Mechanistic links underlying the impact of C-reactive protein on muscle mass in elderly
B Wåhlin-Larsson, DJ Wilkinson… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Mechanisms underlying the relationship between systemic inflammation
and age-related decline in muscle mass are poorly defined. The purpose of this work was to …
and age-related decline in muscle mass are poorly defined. The purpose of this work was to …
Chronic inflammation is associated with low physical function in older adults across multiple comorbidities
TE Brinkley, X Leng, ME Miller… - … Series A: Biomedical …, 2009 - academic.oup.com
Background Chronic subclinical inflammation may contribute to impaired physical function in
older adults; however, more data are needed to determine whether inflammation is a …
older adults; however, more data are needed to determine whether inflammation is a …
Interleukin-6 and C-reactive protein, successful aging, and mortality: the PolSenior study
M Puzianowska-Kuźnicka, M Owczarz… - Immunity & …, 2016 - Springer
Background In the elderly, chronic low-grade inflammation (inflammaging) is a risk factor for
the development of aging-related diseases and frailty. Using data from several thousand …
the development of aging-related diseases and frailty. Using data from several thousand …