Cytokines for evaluation of chronic inflammatory status in ageing research: reliability and phenotypic characterisation

L Koelman, O Pivovarova-Ramich, AFH Pfeiffer… - Immunity & …, 2019 - Springer
Background There is a growing interest in the role of inflammageing for chronic disease
development. Cytokines are potent soluble immune mediators that can be used as target …

Inflammation and frailty measures in older people

RE Hubbard, MS O'Mahony, GM Savva… - Journal of cellular …, 2009 - Wiley Online Library
Inflammation in patients defined as frail by Fried's phenotypic definition may be related to
sarcopenia. This study aimed to investigate inflammation in older patients across different …

Inflammatory response in the elderly

RF Grimble - Current Opinion in Clinical Nutrition & Metabolic …, 2003 - journals.lww.com
Ageing is associated with increased levels of chronic inflammation. This plays a major role
in the decline in immune function and lean body mass. Anti-inflammatory nutrient therapy …

Aging of the endocrine system and its potential impact on sarcopenia

G Vitale, M Cesari, D Mari - European Journal of Internal Medicine, 2016 - Elsevier
Sarcopenia, occurring as a primary consequence of aging, is a progressive generalized
decline of skeletal muscle mass, strength and function. The pathophysiology of sarcopenia …

Aging is associated with circulating cytokine dysregulation

L Álvarez-Rodríguez, M López-Hoyos… - Cellular …, 2012 - Elsevier
PURPOSE: Aging is accompanied by a progressive increase in pro-inflammatory cytokine
status. However, little is known about the development of age-dependent modifications in …

Sarcopenia, a neurogenic syndrome?

P Kwan - Journal of aging research, 2013 - Wiley Online Library
Sarcopenia is an aging‐associated condition, which is currently characterized by the loss of
muscle mass and muscle strength. However, there is no consensus regarding its …

Inflammaging: age and systemic, cellular, and nuclear inflammatory biology in older adults

D Piber, R Olmstead, JHJ Cho… - The Journals of …, 2019 - academic.oup.com
Systemic inflammation is associated with increasing age. Yet, there are limited data about
the association between age and systemic inflammation within older adults, and whether …

[HTML][HTML] Mechanistic links underlying the impact of C-reactive protein on muscle mass in elderly

B Wåhlin-Larsson, DJ Wilkinson… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Mechanisms underlying the relationship between systemic inflammation
and age-related decline in muscle mass are poorly defined. The purpose of this work was to …

Chronic inflammation is associated with low physical function in older adults across multiple comorbidities

TE Brinkley, X Leng, ME Miller… - … Series A: Biomedical …, 2009 - academic.oup.com
Background Chronic subclinical inflammation may contribute to impaired physical function in
older adults; however, more data are needed to determine whether inflammation is a …

Interleukin-6 and C-reactive protein, successful aging, and mortality: the PolSenior study

M Puzianowska-Kuźnicka, M Owczarz… - Immunity & …, 2016 - Springer
Background In the elderly, chronic low-grade inflammation (inflammaging) is a risk factor for
the development of aging-related diseases and frailty. Using data from several thousand …