… 177Lu-labeled somatostatin receptor agonist and antagonist in … and 111In-labeled somatostatin
receptor antagonist OPS201 in … 177Lu-OPS201 targeting somatostatin receptors: in vivo …

… To further evaluate the potential of somatostatin receptor antagonists for radionuclide therapy,
we estimated the organ doses of 90 Y-DOTA-BASS. For these calculations, we assumed …

… of somatostatin cyclized via a disulfide bridge (des-AA 1,2,4,5,12,13 [d-2Nal 8 ]-somatostatin…
and selectivity for the human sst 3 somatostatin receptor subtype transfected in CCL39 cells. …

… agonist at the somatostatin receptor subtype SSTR1. … Very recently, the first potential sst
peptide antagonists have … of the somatostatin receptor subtype 3 is essential for somatostatin-14 …

… The antagonists contain a core structure of a DL-cysteine pair at positions 2 and 7 of the …
converts the full antagonist into a full agonist. All somatostatin receptor subtypes are coupled to …

… somatostatin antagonist and agonist radioligands, with similar binding affinities for somatostatin
receptors, … (1) is based on the somatostatin receptor, and a particularly large number of …

… (b) Amino acid sequence of somatostatin isoforms depicting the cysteine bridge maintaining
its … With respect to the development of SST antagonists, the field has been lagging. The first …

… catalogue of monomeric receptor subtypes isolated and cloned in the past. SRIF analogues
include both peptides and non-peptides, receptor agonists and antagonists. Relatively long …

… agonists for each of the five somatostatin receptors. Also, the first competitive antagonists
for somatostatin receptors have been developed, however, their potencies are still rather low. …

… The development of specific antibodies, agonists and antagonists as well as pan somatostatin
with high affinity for all sst may improve the diagnosis and therapeutic application of …