… of inflammatory diseases. Here we reviewed the characters and functions of macrophage
polarization … TAM polarization is also affected by the spatial location in tumor environment. For …

… Phosphatase and tensin homolog (PTEN) plays a key role in regulating the inflammatory
response through M1-polarization. Mice with a myeloid-specific PTEN knockout have been …

… The role of SHIP-1 in macrophage polarization in case of tumours has not been well
elucidated yet; it can be a therapeutic target of immense importance in cancer drug research. …

… metastasis are termed tumor associated macrophages (TAMs) … functional macrophages and
that anti-inflammatory molecules … that antiinflammatory molecules did not inhibit macrophage …

… Tumors are also considered ‘… inflammatory and imbalanced polarization of macrophages
(7–9). The present review provides an overview of macrophage polarization in inflammatory …

… Macrophages that infiltrate tumor tissues are driven by tumor-derived and … polarized functions
of TAMs integrate them in circuits of subversion of anti-tumor immunity and in inflammatory …

… For decades, solid tumours have been known to be strongly infiltrated by inflammatory
leukocytes, and accumulating evidence has clearly demonstrated, in various mouse and human …

… To fulfill these multiple functions, macrophages are polarized from the inflammation status (…
tumor development, the microenvironmental factors involved in macrophage polarization, and …

… In tumor microenvironments, the macrophages polarization mainly depends on the activity
of local cytokines. In details, Pro-inflammatory M1-like macrophages will be established to …

… These results were consistent with previous observations in tumors, where lactic acid
induced macrophage polarization by relying on MCT uptake or acted as a signal molecule to …