68Ga-DOTA-Tyr3-octreotide PET in neuroendocrine tumors: comparison with somatostatin receptor scintigraphy and CT

M Gabriel, C Decristoforo, D Kendler… - Journal of nuclear …, 2007 - Soc Nuclear Med
… the diagnostic value of a new somatostatin analog, 68 Ga-labeled 1,4,7,… -Tyr 3 -octreotide
( 68 Ga-DOTA-TOC), for PET in patients with known or suspected neuroendocrine tumors. PET

PET imaging of somatostatin receptors using [68GA] DOTA-D-Phe1-Tyr3-octreotide: first results in patients with meningiomas

M Henze, J Schuhmacher, P Hipp… - Journal of Nuclear …, 2001 - Soc Nuclear Med
… ,N‴-tetraacetic-acid-d-Phe 1 -Tyr 3 -octreotide (DOTATOC) was labeled using the positron-…
PET images over 120 min after intravenous injection of 175 MBq [ 68 Ga]DOTATOC in 3

68Ga-DOTA-Tyr3-octreotide PET for assessing response to somatostatin-receptor–mediated radionuclide therapy

M Gabriel, A Oberauer, G Dobrozemsky… - Journal of Nuclear …, 2009 - Soc Nuclear Med
… 68 Ga-labeled 1,4,7,10-tetraazacyclododecane-N,N′,N′′,N′′′-tetraacetic acid-d-Phe
1 -Tyr 3 -octreotide (DOTA-TOC) PET has proven its usefulness in the diagnosis of patients …

Somatostatin receptor PET in neuroendocrine tumours: 68Ga-DOTA0,Tyr3-octreotide versus 68Ga-DOTA0-lanreotide

D Putzer, A Kroiss, D Waitz, M Gabriel… - European journal of …, 2013 - Springer
… 68 Ga-DOTA-TOC PET (n = 2) or in octreotide scintigraphy including SPECT images (… PET
(b) and faint tracer uptake in 18 F-FDG PET (c) in metastases not visible on the octreotide PET

PET imaging of somatostatin receptors: design, synthesis and preclinical evaluation of a novel 18F-labelled, carbohydrated analogue of octreotide

H Wester, M Schottelius, K Scheidhauer… - European journal of …, 2003 - Springer
… Among the sst ligands investigated, [111In]DTPA-octreotide has been … receptor
radiotherapy (PRRT) are promising, and, for example, [90Y]DOTA-Tyr3-octreotide and [177Lu]DOTA-Tyr3

[PDF][PDF] Somatostatin receptor-based imaging and therapy of gastroenteropancreatic neuroendocrine tumors

DJ Kwekkeboom, BL Kam, M Van Essen… - Endocrine-related …, 2010 - researchgate.net
… became the new standard for PET imaging, because the current … such a universal PET
tracer for SRI are [68Ga-DOTA0,Tyr3]… -DOTA0,Tyr3]octreotide and [177Lu-DOTA0,Tyr3]octreotate …

Targeting somatostatin receptors: preclinical evaluation of novel 18F-fluoroethyltriazole-Tyr3-octreotate analogs for PET

J Leyton, L Iddon, M Perumal, B Indrevoll… - Journal of nuclear …, 2011 - Soc Nuclear Med
Tyr 3 -octreotate has been radiolabeled with both 68 Ga and 18 F radioisotopes for PET of
tumors (… The Tyr 3 -octreotate core was selected over octreotide because of its superior sstr-2 …

… somatostatin receptor scintigraphy using in-111-DOTA-lanreotide and in-111-DOTA-Tyr3-octreotide versus F-18-FDG-PET for evaluation of somatostatin receptor …

I Virgolini, P Patri, C Novotny, T Traub, M Leimer… - Annals of oncology, 2001 - Elsevier
… prove the concept of receptor-mediated radiotherapy controlled … -Tyr3-octreotide, versus
I8F-FDG-PET in 218 tumor patients known to bear tumors that frequently express SST receptors. …

Affinity profiles for human somatostatin receptor subtypes SST1–SST5 of somatostatin radiotracers selected for scintigraphic and radiotherapeutic use

JC Reubi, JC Schär, B Waser, S Wenger… - European journal of …, 2000 - Springer
… 1), have been shown in animal models to be more effective for … The recent cloning of several
somatostatin receptor genes … -octreotide or Y-DOTA-octreotide compared with their [Tyr3]-…

Tumor uptake of 68Ga-DOTA-Tyr3-octreotate: animal PET studies of tumor flow and acute somatostatin receptor modulation in the CA20948 rat model

FX Hanin, S Pauwels, A Bol, W Breeman… - Nuclear medicine and …, 2010 - Elsevier
octreotide on [ 68 Ga]-DOTA-Tyr 3 -octreotate uptake in tumors over time. The in vivo exposure
of tumor to cold octreotide … rapid recycling or resynthesis of receptors at the cell surface …