Type III polyketide synthases in natural product biosynthesis
Polyketides represent an important class of biologically active and structurally diverse
compounds in nature. They are synthesized from acyl‐coenzyme A substrates by polyketide …
compounds in nature. They are synthesized from acyl‐coenzyme A substrates by polyketide …
Fungal type III polyketide synthases
M Hashimoto, T Nonaka, I Fujii - Natural Product Reports, 2014 - pubs.rsc.org
Covering: 2005 to 2014 This article covers the literature on fungal type III polyketide
synthases (PKSs) published from 2005 to 2014. Since the first discovery of fungal type III …
synthases (PKSs) published from 2005 to 2014. Since the first discovery of fungal type III …
[HTML][HTML] Exploiting the biosynthetic potential of type III polyketide synthases
Polyketides are structurally and functionally diverse secondary metabolites that are
biosynthesized by polyketide synthases (PKSs) using acyl-CoA precursors. Recent studies …
biosynthesized by polyketide synthases (PKSs) using acyl-CoA precursors. Recent studies …
Type III polyketide synthases in microorganisms
Y Katsuyama, Y Ohnishi - Methods in Enzymology, 2012 - Elsevier
Type III polyketide synthases (PKSs) are simple homodimers of ketosynthases which
catalyze the condensation of one to several molecules of extender substrate onto a starter …
catalyze the condensation of one to several molecules of extender substrate onto a starter …
Recent advances in the biosynthesis of unusual polyketide synthase substrates
L Ray, BS Moore - Natural product reports, 2016 - pubs.rsc.org
Covering: 2003 to July 2015 for polyketide synthase starter units and 2012 to September
2015 for polyketide synthase extender units This highlight provides an overview of recent …
2015 for polyketide synthase extender units This highlight provides an overview of recent …
Advances in cloning, functional analysis and heterologous expression of fungal polyketide synthase genes
J Schümann, C Hertweck - Journal of biotechnology, 2006 - Elsevier
Fungal polyketides comprise a diverse group of secondary metabolites that play an
important role for drug discovery, as pigments, and as mycotoxins. Their biosynthesis is …
important role for drug discovery, as pigments, and as mycotoxins. Their biosynthesis is …
Bacterial type III polyketide synthases: phylogenetic analysis and potential for the production of novel secondary metabolites by heterologous expression in …
F Gross, N Luniak, O Perlova, N Gaitatzis… - Archives of …, 2006 - Springer
Type III polyketide synthases (PKS) were regarded as typical for plant secondary
metabolism before they were found in microorganisms recently. Due to microbial genome …
metabolism before they were found in microorganisms recently. Due to microbial genome …
The chalcone synthase superfamily of type III polyketide synthases
MB Austin, JP Noel - Natural product reports, 2003 - pubs.rsc.org
Covering 1970–2001This review covers the functionally diverse type III polyketide synthase
(PKS) superfamily of plant and bacterial biosynthetic enzymes, from the discovery of …
(PKS) superfamily of plant and bacterial biosynthetic enzymes, from the discovery of …
Discovery of a new bacterial polyketide biosynthetic pathway
BS Moore, JN Hopke - ChemBioChem, 2001 - Wiley Online Library
Biochemically and phylogenetically unrelated to the well‐characterized microbial polyketide
synthases (PKSs), which are responsible for the biosynthesis of many clinically important …
synthases (PKSs), which are responsible for the biosynthesis of many clinically important …
Expanding the biosynthetic repertoire of plant type III polyketide synthases by altering starter molecule specificity
Type III polyketide synthases (PKS) generate an array of natural products by condensing
multiple acetyl units derived from malonyl-CoA to thioester-linked starter molecules …
multiple acetyl units derived from malonyl-CoA to thioester-linked starter molecules …