Many bacterial and fungal secondary metabolites are produced by polyketide synthases
(PKS) and non-ribosomal peptide synthetases (NRPS). Recently, it has been discovered …

Background: Myxobacteria have been well established as a potent source for natural
products with biological activity. They produce a considerable variety of compounds which …

Myxobacterial strains producing polyketides (PKs) assumed to be biosynthesized by a type I
polyketide synthase (PKS) were analysed. Myxobacteria also produce a variety of …

Covering: bacterial genome sequences to 2005 and post-genomic literature to June 2006 A
total of 223 complete bacterial genomes are analyzed, with 281 citations, for the presence of …

Myxobacteria are prolific producers of a wide variety of secondary metabolites. The vast
majority of these compounds are complex polyketides which are biosynthesised by …

The myxobacterium Stigmatella aurantiaca DW4/3–1 harbours an astonishing variety of
secondary metabolic gene clusters, at least two of which were found by gene inactivation …

Non-ribosomal peptide synthetases (NRPS) and type-I polyketide synthases (PKS-I) are
multimodular enzymes involved in biosynthesis of oligopeptide and polyketide secondary …

Enormous progress in the field of polyketide biosynthesis has led to the establishment of
rules for general text book biosynthetic logic and consequently to the assumption that …

The high G+ C content and large genome size make the sequencing and assembly of
Streptomyces genomes more difficult than for other bacteria. Many pharmaceutically …

Nonribosomal peptide synthetases (NRPS) and type I polyketide synthases (PKS-I) are
biosynthetic systems involved in the synthesis of a large number of important biologically …