Fungal polyketide synthases are responsible for the biosynthesis of several mycotoxins and
other secondary metabolites. The aim of our work was to investigate the diversity of …

Analysis of fungal polyketide synthase gene sequences suggested that these might be
divided into two subclasses, designated WA-type and MSAS-type. Two pairs of degenerate …

The polyketide synthase gene pksM was detected in the genomic DNA library of Aspergillus
terreus by hybridization with the 6-methylsalicylic acid synthase (6-MSAS) gene of …

Secondary metabolites are small molecules that show large structural diversity and a broad
range of bioactivities. Some metabolites are attractive as drugs or pigments while others act …

The diversity of polyketide synthase (PKS) genes in Aspergillus ochraceus NRRL 3174 and
Aspergillus carbonarius 2Mu134 has been investigated using different primer pairs …

The genome sequencing of Aspergillus species including A. nidulans reveals that the
products of many of the secondary metabolism pathways in these fungi have not been …

Where does one draw the line between primary and secondary metabolism? The answer
depends on the perspective. Microbial secondary metabolites (SMs) were at first believed …

Entomopathogenic fungi are able to invade and kill insects. Various secondary metabolites
can mediate the interaction of a fungal pathogen with an insect host and also help the …

Production of polyketides is accomplished through complex enzymes known as polyketide
synthases (PKS); these enzymes have highly conserved domains that might be useful in …

Identification of genes encoding type III polyketide synthase (PKS) superfamily members in
the industrially useful filamentous fungus, Aspergillus oryzae, revealed that their distribution …