Aspergillus species have the ability to produce a wide range of secondary metabolites
including polyketides that are generated by multi-domain polyketide synthases (PKSs) …

Nonribosomal peptide synthetases (NRPS) and type I polyketide synthases (PKS-I) are
biosynthetic systems involved in the synthesis of a large number of important biologically …

Fungal type I polyketide (PK) compounds are highly valuable for medical treatment and
extremely diverse in structure, partly because of the enzymatic activities of reducing domains …

Fungal polyketide synthase (PKS)–nonribosomal peptide synthetase (NRPS) hybrids are
key enzymes for synthesizing structurally diverse hybrid natural products (NPs) with …

Fungal polyketide synthase–nonribosomal peptide synthetase (PKS–NRPS) hybrids
manufacture a wide range of structurally diverse secondary metabolites that play an eminent …

The widely found fungal iterative PKS-NRPS hybrid megasynthetases are highly
programmed biosynthetic machines involved in the synthesis of 3-acyltetramic acids and …

Type III polyketide synthases (PKSs) produce secondary metabolites with diverse biological
activities, including antimicrobials. While they have been extensively studied in plants and …

Covering: 2005 to 2014 This article covers the literature on fungal type III polyketide
synthases (PKSs) published from 2005 to 2014. Since the first discovery of fungal type III …

Microorganisms have invented many devious ways to thwart their foes and survive in
adverse environments. Non-motile microbes, especially ones that inhabit soil and marine …

Aryl-aldehydes are a common feature in fungal polyketides, which are considered to be
exclusively generated by the R domain of nonreducing polyketide synthases (NR-PKSs) …