Species of the fungus Fusarium collectively cause disease on almost all crop plants and
produce numerous natural products (NPs), including some of the mycotoxins of greatest …

Covering: 1999 up to 2021 Fungal polyketides encompass a range of structurally diverse
molecules with a wide variety of biological activities. The giant multifunctional enzymes that …

Fungal genome sequencing has revealed many genes coding for biosynthetic enzymes,
including polyketide synthases and nonribosomal peptide synthetases. However …

Fungal polyketides have huge structural diversity from simple aromatics to highly modified
complex reduced-type compounds. Despite such diversty, single modular iterative type I …

Using an approach based on polymerase chain reaction (PCR), we examined the diversity
of polyketide synthase (PKS) genes present in 160 marine fungal isolates, representing 142 …

Fungi produce a wide variety of biologically active compounds. Among these, the
polyketides form a large and structurally diverse group. These compounds are synthesised …

Non-ribosomal peptide (NRP) synthesis in fungi requires a ready supply of proteogenic and
non-proteogenic amino acids which are subsequently incorporated into the nascent NRP via …

Highly reducing polyketide synthases (HR‐PKSs) produce structurally diverse polyketides
(PKs). The PK diversity is constructed by a variety of factors, including the β‐keto processing …

Background Filamentous fungi produce a vast amount of bioactive secondary metabolites
(SMs) synthesized by eg hybrid polyketide synthase-nonribosomal peptide synthetase …

Non-ribosomal peptide synthetases (NRPSs) and polyketide synthases (PKSs) present in
bacteria and fungi are the major multi-modular enzyme complexes which synthesize …