Polyketides draw much attention because of their potential use in pharmaceutical and
biotechnological applications. This study identifies an abundant pool of polyketide synthase …

Fungal polyketides display complex structures and variously biological activities. Their
biosynthetic pathways generally contain novel enzyme-catalyzed reactions. This review …

Using an approach based on polymerase chain reaction (PCR), we examined the diversity
of polyketide synthase (PKS) genes present in 160 marine fungal isolates, representing 142 …

Production of polyketides is accomplished through complex enzymes known as polyketide
synthases (PKS); these enzymes have highly conserved domains that might be useful in …

Fungal hybrid polyketide synthase-nonribosomal peptide synthetases (PKS-NRPSs)
significantly expand the diversity and functionalities of polyketide metabolites by fusing …

Polyketides represent an important class of biologically active and structurally diverse
compounds in nature. They are synthesized from acyl‐coenzyme A substrates by polyketide …

Entomopathogenic fungi are able to invade and kill insects. Various secondary metabolites
can mediate the interaction of a fungal pathogen with an insect host and also help the …

Fungal polyketide synthase–nonribosomal peptide synthetase (PKS–NRPS) hybrids have
been characterized to produce polyketide–amino acid compounds with striking structural …

Fungal polyketides comprise a diverse group of secondary metabolites that play an
important role for drug discovery, as pigments, and as mycotoxins. Their biosynthesis is …

Fungal type I polyketide (PK) compounds are highly valuable for medical treatment and
extremely diverse in structure, partly because of the enzymatic activities of reducing domains …