Applying multi-omics techniques to the discovery of biomarkers for acute aortic dissection

X Hao, S Cheng, B Jiang, S Xin - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Acute aortic dissection (AAD) is a cardiovascular disease that manifests suddenly and
fatally. Due to the lack of specific early symptoms, many patients with AAD are often …

[HTML][HTML] A proteome-wide screen identifies the calcium binding proteins, S100A8/S100A9, as clinically relevant therapeutic targets in aortic dissection

H Jiang, Y Zhao, M Su, L Sun, M Chen, Z Zhang… - Pharmacological …, 2024 - Elsevier
Aortic dissection (AD) is a fatal cardiovascular disease with limited pharmacotherapies. To
discover novel therapeutic targets for AD, the present study was conducted on ascending …

A multi-method approach towards understanding the pathophysiology of aortic dissections–the complementary role of in-silico, in-vitro and in-vivo information

PA Rudenick, M Bordone, BH Bijnens… - Statistical Atlases and …, 2010 - Springer
Management and follow-up of chronic aortic dissections continues to be a clinical challenge
due to progressive aortic dilatation. To predict dilatation, guidelines suggest follow-up of the …

Biomarkers for diagnosis and prognostic stratification of aortic dissection: challenges and perspectives

F Morello, P Piler, M Novak, P Kruzliak - Biomarkers in medicine, 2014 - Taylor & Francis
Aortic dissection (AD) is a severe vascular disease associated with major morbidity and
mortality. The diagnosis of AD requires the performance of urgent aortic imaging exams …

Pathway analysis of differentially expressed genes in patients with acute aortic dissection

SA Mohamed, HH Sievers, T Hanke… - Biomarker …, 2009 - journals.sagepub.com
Background Acute aortic dissection (AAD) is a life-threatening condition with high mortality
and a relatively unclarified pathophysiological mechanism. Although differentially expressed …

Histopathological and biomechanical properties of the aortic wall in 2 patients with chronic type A aortic dissection

A Emmott, I El-Hamamsy, RL Leask - Cardiovascular Pathology, 2017 - Elsevier
Type A aortic dissection is an acute condition that requires urgent surgical intervention.
However, in a subset of patients, aortic dissections go undiagnosed and become chronic …

Arterial dissections: Common features and new perspectives

M Bax, V Romanov, K Junday… - Frontiers in …, 2022 - frontiersin.org
Arterial dissections, which involve an abrupt tear in the wall of a major artery resulting in the
intramural accumulation of blood, are a family of catastrophic disorders causing major …

Biomarkers in aortic dissection

D Wen, XL Zhou, JJ Li, RT Hui - Clinica chimica acta, 2011 - Elsevier
Aortic dissection (AD) is a severe cardiovascular disease with high mortality and morbidity,
which is characterized by acute onset and rapid progress. Mechanically, it has been …

Aortic dissection: global epidemiology

J Yin, F Liu, J Wang, P Yuan, S Wang, W Guo - Cardiology Plus, 2022 - journals.lww.com
Aortic dissection is a highly fatal disease with limited predictability requiring emergency
response. It remains a challenging clinical problem and has a reported lower 5-year survival …

Biomarkers for the diagnosis of aortic dissection

A Segreto, A Chiusaroli… - Journal of Cardiac …, 2014 - Wiley Online Library
Biomarkers for the Diagnosis of Aortic Dissection - Segreto - 2014 - Journal of Cardiac Surgery
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