Aortic dissection (AD) is a fatal cardiovascular disease with limited pharmacotherapies. To
discover novel therapeutic targets for AD, the present study was conducted on ascending …

Background: Thoracic aortic dissection (TAD) is one of the cardiovascular diseases with
high incidence and fatality rates. Vascular smooth muscle cells (VSMCs) play a vital role in …

Aims Acute aortic dissection (AAD) is a life-threatening disease with high morbidity and
mortality. Previous studies have showed that vascular smooth muscle cell (VSMC) …

Objective To identify the feature of N6-methyladenosine (m6A) methylation modification
genes in acute aortic dissection (AAD) and explore their relationships with immune …

Background and aims Acute aortic dissection (AAD) is a serious life-threatening
cardiovascular condition. It is necessary to find rapid and accurate biomarkers for the …

There is no treatment for acute aortic dissection (AAD) targeting inflammatory cells. We
aimed to identify the new therapeutic targets associated with inflammatory cells. We …

Macrophages play an important role in the progression of sporadic acute type A aortic
dissection (ATAAD). The aim of this study was to characterize the cellular heterogeneity of …

Macrophage class A1 scavenger receptor (SR-A1) is a pattern recognition receptor with an
anti-inflammatory feature in cardiovascular diseases. However, its role in acute aortic …

Aortic dissection (AD) is a lethal aortic pathology without effective medical treatments since
the underlying pathological mechanisms responsible for AD remain elusive. Matrix …

Abstract Background and Aims Stanford type A aortic dissection (AD) is a degenerative
aortic remodelling disease marked by an exceedingly high mortality without effective …