Physiological and therapeutic roles of peroxisome proliferator-activated receptors
J Berger, JA Wagner - Diabetes technology & therapeutics, 2002 - liebertpub.com
The peroxisome proliferator-activated receptors (PPARs) are a group of nuclear receptor
isoforms, including PPAR γ, PPAR α, and PPAR δ, encoded by different genes. PPARs are …
isoforms, including PPAR γ, PPAR α, and PPAR δ, encoded by different genes. PPARs are …
Peroxisome proliferator-activated receptor beta/delta (PPARβ/δ) acts as regulator of metabolism linked to multiple cellular functions
KD Wagner, N Wagner - Pharmacology & therapeutics, 2010 - Elsevier
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors. They function as
ligand activated transcription factors. They exist in three isoforms, PPARα, PPARβ (formerly …
ligand activated transcription factors. They exist in three isoforms, PPARα, PPARβ (formerly …
The mechanisms of action of PPARs
J Berger, DE Moller - Annual review of medicine, 2002 - annualreviews.org
▪ Abstract The peroxisome proliferator-activated receptors (PPARs) are a group of three
nuclear receptor isoforms, PPARγ, PPARα, and PPARδ, encoded by different genes. PPARs …
nuclear receptor isoforms, PPARγ, PPARα, and PPARδ, encoded by different genes. PPARs …
Pleiotropic actions of peroxisome proliferator–activated receptors in lipid metabolism and atherosclerosis
Peroxisome proliferator–activated receptors (PPARs) are nuclear receptors activated by fatty
acids and derivatives. Although PPARα mediates the hypolipidemic action of fibrates …
acids and derivatives. Although PPARα mediates the hypolipidemic action of fibrates …
Biology and therapeutic applications of peroxisome proliferator-activated receptors
MP Menendez-Gutierrez, T Roszer… - Current topics in …, 2012 - ingentaconnect.com
Peroxisome proliferator-activated receptors (PPARs) are ligand dependent transcription
factors. The three mammalian PPARs are key regulators of fatty acid and lipoprotein …
factors. The three mammalian PPARs are key regulators of fatty acid and lipoprotein …
[PDF][PDF] Peroxisome proliferator-activated receptors (PPARS): a target with a broad therapeutic potential for human diseases: an overview
Increasing attention has been focused on the role of peroxisome proliferator-activated
receptors (PPARs) in the past decade. Compelling data have begun to unite work from …
receptors (PPARs) in the past decade. Compelling data have begun to unite work from …
Significance of peroxisome proliferator-activated receptors in the cardiovascular system in health and disease
E Robinson, DJ Grieve - Pharmacology & therapeutics, 2009 - Elsevier
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated nuclear
transcription factors that belong to the nuclear receptor superfamily. Three isoforms of PPAR …
transcription factors that belong to the nuclear receptor superfamily. Three isoforms of PPAR …
The biology of peroxisome proliferator-activated receptors: relationship with lipid metabolism and insulin sensitivity
P Ferré - Diabetes, 2004 - Am Diabetes Assoc
Peroxisome proliferator-activated receptors (PPARs) are transcription factors belonging to
the superfamily of nuclear receptors. Three isoforms (α, δ, and γ) have been described. They …
the superfamily of nuclear receptors. Three isoforms (α, δ, and γ) have been described. They …
Peroxisome proliferator–activated receptors as transcriptional nodal points and therapeutic targets
Peroxisome proliferator–activated receptors (PPARs) are ligand-activated transcription
factors involved in the transcriptional regulation of key metabolic pathways such as lipid …
factors involved in the transcriptional regulation of key metabolic pathways such as lipid …
Physiological functions of peroxisome proliferator-activated receptor β
JG Neels, PA Grimaldi - Physiological reviews, 2014 - journals.physiology.org
The peroxisome proliferator-activated receptors, PPARα, PPARβ, and PPARγ, are a family of
transcription factors activated by a diversity of molecules including fatty acids and fatty acid …
transcription factors activated by a diversity of molecules including fatty acids and fatty acid …
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