From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions
JN Feige, L Gelman, L Michalik, B Desvergne… - Progress in lipid …, 2006 - Elsevier
Peroxisome proliferator-activated receptors (PPARs) compose a family of three nuclear
receptors which act as lipid sensors to modulate gene expression. As such, PPARs are …
receptors which act as lipid sensors to modulate gene expression. As such, PPARs are …
PPARs: fatty acid sensors controlling metabolism
L la Cour Poulsen, M Siersbæk, S Mandrup - Seminars in cell & …, 2012 - Elsevier
The peroxisome proliferator activated receptors (PPARs) are nuclear receptors that play key
roles in the regulation of lipid metabolism, inflammation, cellular growth, and differentiation …
roles in the regulation of lipid metabolism, inflammation, cellular growth, and differentiation …
Transcription coactivators for peroxisome proliferator-activated receptors
S Yu, JK Reddy - Biochimica et Biophysica Acta (BBA)-molecular and …, 2007 - Elsevier
Peroxisome proliferator-activated receptors (PPARs) regulate diverse biological processes
such as development, differentiation, neoplastic conversion, inflammation and wound …
such as development, differentiation, neoplastic conversion, inflammation and wound …
Kinase signaling cascades that modulate peroxisome proliferator-activated receptors
L Gelman, L Michalik, B Desvergne, W Wahli - Current Opinion in Cell …, 2005 - Elsevier
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors involved in lipid
and glucose homeostasis, inflammation and wound healing. In addition to ligand binding …
and glucose homeostasis, inflammation and wound healing. In addition to ligand binding …
[HTML][HTML] PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation
Cells are constantly exposed to a large variety of lipids. Traditionally, these molecules were
thought to serve as simple energy storing molecules. More recently it has been realized that …
thought to serve as simple energy storing molecules. More recently it has been realized that …
Peroxisome proliferator-activated receptor α target genes
Peroxisome proliferator-activated receptors (PPARs) are nuclear proteins that belong to the
superfamily of nuclear hormone receptors. They mediate the effects of small lipophilic …
superfamily of nuclear hormone receptors. They mediate the effects of small lipophilic …
Be fit or be sick: peroxisome proliferator-activated receptors are down the road
B Desvergne, L Michalik, W Wahli - Molecular Endocrinology, 2004 - academic.oup.com
Investigating metabolism by unveiling the functions of the nuclear receptors peroxisome
proliferator-activated receptors (PPARs) in the numerous intricate pathways ensuring energy …
proliferator-activated receptors (PPARs) in the numerous intricate pathways ensuring energy …
Peroxisome proliferator-activated receptors: from transcriptional control to clinical practice
Peroxisome proliferator-activated receptors (PPARs) are lipid-activated transcription factors
that control energy homeostasis through genomic actions. Over the past few years …
that control energy homeostasis through genomic actions. Over the past few years …
Peroxisome proliferator-activated receptors and the regulation of mammalian lipid metabolism
SA Smith - Biochemical Society Transactions, 2002 - portlandpress.com
Peroxisome proliferator-activated receptors (PPARs) are members of the superfamily of
ligand-activated nuclear transcription factors. Three PPAR subtypes, PPARα, PPARδ …
ligand-activated nuclear transcription factors. Three PPAR subtypes, PPARα, PPARδ …
An update on the mechanisms of action of the peroxisome proliferator-activated receptors (PPARs) and their roles in inflammation and cancer
L Gelman, JC Fruchart, J Auwerx - Cellular and Molecular Life Sciences …, 1999 - Springer
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors and have been
initially described as molecular targets for compounds which induce peroxisome …
initially described as molecular targets for compounds which induce peroxisome …