Long-chain polyunsaturated fatty acids regulation of PPARs, signaling: Relationship to tissue development and aging

F Echeverría, M Ortiz, R Valenzuela… - … Leukotrienes and Essential …, 2016 - Elsevier
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that function as
ligand-dependent transcription factors that can be activated by different types of fatty acids …

PPARs: fatty acid sensors controlling metabolism

L la Cour Poulsen, M Siersbæk, S Mandrup - Seminars in cell & …, 2012 - Elsevier
The peroxisome proliferator activated receptors (PPARs) are nuclear receptors that play key
roles in the regulation of lipid metabolism, inflammation, cellular growth, and differentiation …

[HTML][HTML] PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation

T Varga, Z Czimmerer, L Nagy - … et Biophysica Acta (BBA)-Molecular Basis …, 2011 - Elsevier
Cells are constantly exposed to a large variety of lipids. Traditionally, these molecules were
thought to serve as simple energy storing molecules. More recently it has been realized that …

PPARs: transcriptional effectors of fatty acids and their derivatives

AK Hihi, L Michalik, W Wahli - Cellular and Molecular Life Sciences, 2002 - Springer
Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that
mediate the effects of fatty acids and their derivatives at the transcriptional level. These …

[PDF][PDF] Multifaceted roles of peroxisome proliferator-activated receptors (PPARs) at the cellular and whole organism levels.

A Yessoufou, W Wahli - Swiss medical weekly, 2010 - serval.unil.ch
Chronic disorders, such as obesity, diabetes, inflammation, non-alcoholic fatty liver disease
and atherosclerosis, are related to alterations in lipid and glucose metabolism, in which …

Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation

G Chinetti, JC Fruchart, B Staels - Inflammation research, 2000 - Springer
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription
factors belonging to the nuclear receptor family. PPARs function as regulators of lipid and …

The integration of lipid-sensing and anti-inflammatory effects: how the PPARs play a role in metabolic balance

AVW Nunn, J Bell, P Barter - Nuclear receptor, 2007 - Springer
The peroxisomal proliferating-activated receptors (PPARs) are lipid-sensing transcription
factors that have a role in embryonic development, but are primarily known for modulating …

From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions

JN Feige, L Gelman, L Michalik, B Desvergne… - Progress in lipid …, 2006 - Elsevier
Peroxisome proliferator-activated receptors (PPARs) compose a family of three nuclear
receptors which act as lipid sensors to modulate gene expression. As such, PPARs are …

Regulation of lipid and lipoprotein metabolism by PPAR activators

P Gervois, IP Torra, JC Fruchart, B Staels - 2000 - degruyter.com
The peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription
factors belonging to the nuclear hormone receptor superfamily. PPARα, the first identified …

PPARs and metabolic disorders associated with challenged adipose tissue plasticity

P Corrales, A Vidal-Puig, G Medina-Gómez - International Journal of …, 2018 - mdpi.com
Peroxisome proliferator-activated receptors (PPARs) are members of a family of nuclear
hormone receptors that exert their transcriptional control on genes harboring PPAR …