PPARs at the crossroads of lipid signaling and inflammation
W Wahli, L Michalik - Trends in Endocrinology & Metabolism, 2012 - cell.com
Nuclear receptors (NRs) are ligand-dependent transcription factors whose activation affects
genes controlling vital processes. Among them, the peroxisome proliferator-activated …
genes controlling vital processes. Among them, the peroxisome proliferator-activated …
Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation
G Chinetti, JC Fruchart, B Staels - Inflammation research, 2000 - Springer
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription
factors belonging to the nuclear receptor family. PPARs function as regulators of lipid and …
factors belonging to the nuclear receptor family. PPARs function as regulators of lipid and …
PPARs and other nuclear receptors in inflammation
G Rizzo, S Fiorucci - Current opinion in pharmacology, 2006 - Elsevier
Inflammation is a central component of several chronic human diseases, including
atherosclerosis and type 2 diabetes. Several nuclear receptors repress inflammatory …
atherosclerosis and type 2 diabetes. Several nuclear receptors repress inflammatory …
Molecular Actions of PPARα in Lipid Metabolism and Inflammation
N Bougarne, B Weyers, SJ Desmet, J Deckers… - Endocrine …, 2018 - academic.oup.com
Peroxisome proliferator–activated receptor α (PPAR α) is a nuclear receptor of clinical
interest as a drug target in various metabolic disorders. PPAR α also exhibits marked anti …
interest as a drug target in various metabolic disorders. PPAR α also exhibits marked anti …
Emerging roles of peroxisome proliferator-activated receptor-β/δ in inflammation
D Bishop-Bailey, J Bystrom - Pharmacology & therapeutics, 2009 - Elsevier
Peroxisome proliferator-activated receptor (PPAR)-β/δ is a member of the PPAR nuclear
hormone receptor family. The PPARs are a family of 3 ligand-activated transcription factors …
hormone receptor family. The PPARs are a family of 3 ligand-activated transcription factors …
PPARs in diseases: control mechanisms of inflammation
R Kostadinova, W Wahli… - Current medicinal …, 2005 - ingentaconnect.com
The three isotypes of peroxisome proliferator-activated receptors (PPARs), PPARa, β/δ and
γ, are ligand-inducible transcription factors that belong to the nuclear hormone receptor …
γ, are ligand-inducible transcription factors that belong to the nuclear hormone receptor …
[HTML][HTML] PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation
Cells are constantly exposed to a large variety of lipids. Traditionally, these molecules were
thought to serve as simple energy storing molecules. More recently it has been realized that …
thought to serve as simple energy storing molecules. More recently it has been realized that …
PPARs as drug targets to modulate inflammatory responses?
R Genolet, W Wahli, L Michalik - Current Drug Targets …, 2004 - ingentaconnect.com
The three peroxisome proliferator-activated receptors (PPARs) isotypes (PPARα, β/δ and γ)
belong to the nuclear hormone receptor family. During the last decade, they have been …
belong to the nuclear hormone receptor family. During the last decade, they have been …
PPARs and lipid ligands in inflammation and metabolism
Peroxisome proliferator-activated receptors (PPARs) belong to a family of ligand-activated
nuclear receptors that includes the estrogen, thyroid hormone, and glucocorticoid receptors …
nuclear receptors that includes the estrogen, thyroid hormone, and glucocorticoid receptors …
Peroxisome proliferator-activated receptors and inflammation
LA Moraes, L Piqueras, D Bishop-Bailey - Pharmacology & therapeutics, 2006 - Elsevier
Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone
receptors family. PPARs are a family of 3 ligand-activated transcription factors: PPARα …
receptors family. PPARs are a family of 3 ligand-activated transcription factors: PPARα …