Peroxisome proliferator‐activated receptor‐γ: too much of a good thing causes harm
The nuclear receptor peroxisome proliferator‐activated receptor‐γ (PPARγ) helps to
translate 'what you eat'into 'what you are'because it allows dietary fatty acids (PPARγ …
translate 'what you eat'into 'what you are'because it allows dietary fatty acids (PPARγ …
The many faces of PPARγ
M Lehrke, MA Lazar - Cell, 2005 - cell.com
In an era marked by the increasing prevalence of obesity, diabetes, and cardiovascular
disease, the nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ) has …
disease, the nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ) has …
Peroxisome proliferator‐activated receptor γ: the more the merrier?
CA Argmann, TA Cock, J Auwerx - European journal of clinical …, 2005 - Wiley Online Library
The consequence of activating the nuclear hormone receptor, peroxisome proliferator‐
activated receptor gamma (PPARγ), which coordinates adipocyte differentiation, validates …
activated receptor gamma (PPARγ), which coordinates adipocyte differentiation, validates …
Peroxisome proliferator-activated receptor-γ calls for activation in moderation: lessons from genetics and pharmacology
C Knouff, J Auwerx - Endocrine reviews, 2004 - academic.oup.com
The peroxisome proliferator-activated receptor γ (PPARγ) is a prototypical member of the
nuclear receptor superfamily and integrates the control of energy, lipid, and glucose …
nuclear receptor superfamily and integrates the control of energy, lipid, and glucose …
PPARγ, 10 years later
MA Lazar - Biochimie, 2005 - Elsevier
It is now over 10 years since the discovery of peroxisome proliferator activated receptor γ
(PPARγ) and its unique role in adipogenesis. The subsequent identification of PPARγ as the …
(PPARγ) and its unique role in adipogenesis. The subsequent identification of PPARγ as the …
PPARγ as a metabolic regulator: insights from genomics and pharmacology
DB Savage - Expert reviews in molecular medicine, 2005 - cambridge.org
Since its identification in the early 1990s, peroxisome-proliferator-activated receptor γ
(PPARγ), a nuclear hormone receptor, has attracted tremendous scientific and clinical …
(PPARγ), a nuclear hormone receptor, has attracted tremendous scientific and clinical …
Peroxisome proliferator-activated receptors as attractive antiobesity targets.
F Zhang, B Lavan, FM Gregoire - Drug News & Perspectives, 2004 - europepmc.org
The peroxisome proliferator-activated receptors (PPARs) alpha, delta and gamma are a
group of ligand-activated transcription factors that function as lipid sensors and govern …
group of ligand-activated transcription factors that function as lipid sensors and govern …
The role of peroxisome proliferator-activated receptor gamma in diabetes and obesity
FS Celi, AR Shuldiner - Current diabetes reports, 2002 - Springer
Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor, which
upon activation with various natural and synthetic ligands, stimulates the transcription of …
upon activation with various natural and synthetic ligands, stimulates the transcription of …
Peroxisome proliferator-activated receptor-γ: a versatile metabolic regulator
S Rocchi, J Auwerx - Annals of medicine, 1999 - Taylor & Francis
The peroxisome proliferator-activated receptor-γ (PPARγ) is a nuclear receptor that controls
the expression of a large array of genes involved in adipocyte differentiation, lipid storage …
the expression of a large array of genes involved in adipocyte differentiation, lipid storage …
PPAR-γ: a thrifty transcription factor
J Auwerx, TA Cock, C Knouff - Nuclear Receptor Signaling, 2003 - journals.sagepub.com
The peroxisome proliferator-activated receptor-γ (PPAR-γ) is a prototypical metabolic
nuclear receptor that acts as a lipid sensor, integrating the homeostatic control of energy …
nuclear receptor that acts as a lipid sensor, integrating the homeostatic control of energy …