PPARs: nuclear receptors controlled by, and controlling, nutrient handling through nuclear and cytosolic signaling
M Moreno, A Lombardi, E Silvestri, R Senese… - PPAR …, 2010 - Wiley Online Library
Peroxisome proliferator‐activated receptors (PPARs), which are known to regulate lipid
homeostasis, are tightly controlled by nutrient availability, and they control nutrient handling …
homeostasis, are tightly controlled by nutrient availability, and they control nutrient handling …
Ligand-dependent and-independent regulation of PPARγ and orphan nuclear receptors
HE Xu, Y Li - Science Signaling, 2008 - science.org
Peroxisome proliferator–activated receptor γ (PPARγ) is considered to be a ligand-activated
nuclear receptor with essential roles in adipogenesis, glucose and lipid homeostasis, and …
nuclear receptor with essential roles in adipogenesis, glucose and lipid homeostasis, and …
The nuclear receptor PPARγ-bigger than fat
SA Kliewer, TM Willson - Current opinion in genetics & development, 1998 - Elsevier
Work reported over the past year has provided insights into the mechanisms whereby ligand
activation of the nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ) …
activation of the nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ) …
PPARs: diverse regulators in energy metabolism and metabolic diseases
YX Wang - Cell research, 2010 - nature.com
The nuclear receptor PPARs are fundamentally important for energy homeostasis. Through
their distinct yet overlapping functions and tissue distribution, the PPARs regulate many …
their distinct yet overlapping functions and tissue distribution, the PPARs regulate many …
PPARs: fatty acid sensors controlling metabolism
L la Cour Poulsen, M Siersbæk, S Mandrup - Seminars in cell & …, 2012 - Elsevier
The peroxisome proliferator activated receptors (PPARs) are nuclear receptors that play key
roles in the regulation of lipid metabolism, inflammation, cellular growth, and differentiation …
roles in the regulation of lipid metabolism, inflammation, cellular growth, and differentiation …
From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions
JN Feige, L Gelman, L Michalik, B Desvergne… - Progress in lipid …, 2006 - Elsevier
Peroxisome proliferator-activated receptors (PPARs) compose a family of three nuclear
receptors which act as lipid sensors to modulate gene expression. As such, PPARs are …
receptors which act as lipid sensors to modulate gene expression. As such, PPARs are …
PPAR-γ: a thrifty transcription factor
J Auwerx, TA Cock, C Knouff - Nuclear Receptor Signaling, 2003 - journals.sagepub.com
The peroxisome proliferator-activated receptor-γ (PPAR-γ) is a prototypical metabolic
nuclear receptor that acts as a lipid sensor, integrating the homeostatic control of energy …
nuclear receptor that acts as a lipid sensor, integrating the homeostatic control of energy …
Nuclear Receptor Cofactors in PPARγ‐Mediated Adipogenesis and Adipocyte Energy Metabolism
E Powell, P Kuhn, W Xu - PPAR research, 2007 - Wiley Online Library
Transcriptional cofactors are integral to the proper function and regulation of nuclear
receptors. Members of the peroxisome proliferator‐activated receptor (PPAR) family of …
receptors. Members of the peroxisome proliferator‐activated receptor (PPAR) family of …
Transcriptional control of physiological and pathological processes by the nuclear receptor PPARβ/δ
Peroxisome proliferator-activated receptors (PPARs) are a class of transcription factors that
belong to the nuclear hormone receptor superfamily, and their activities are dependent on …
belong to the nuclear hormone receptor superfamily, and their activities are dependent on …
The Role of PPARα Activation in Liver and Muscle
L Burri, GH Thoresen, RK Berge - PPAR research, 2010 - Wiley Online Library
PPARα is one of three members of the soluble nuclear receptor family called peroxisome
proliferator‐activated receptor (PPAR). It is a sensor for changes in levels of fatty acids and …
proliferator‐activated receptor (PPAR). It is a sensor for changes in levels of fatty acids and …