PPARγ and its ligands: therapeutic implications in cardiovascular disease
The relevance of PPARγ (peroxisome-proliferator-activated receptor γ) as an important
therapeutic target for the treatment of diabetes arises from its hypoglycaemic effects in …
therapeutic target for the treatment of diabetes arises from its hypoglycaemic effects in …
PPARγ and Its Role in Cardiovascular Diseases
M Chandra, S Miriyala, M Panchatcharam - PPAR research, 2017 - Wiley Online Library
Peroxisome proliferator‐activated receptor Gamma (PPARγ), a ligand‐activated
transcription factor, has a role in various cellular functions as well as glucose homeostasis …
transcription factor, has a role in various cellular functions as well as glucose homeostasis …
Peroxisome proliferator-activated receptor (PPAR) gamma agonists as therapeutic agents for cardiovascular disorders: focus on atherosclerosis
EA Ivanova, VA Myasoedova… - Current …, 2017 - ingentaconnect.com
Peroxisome proliferation-activated receptors (PPARs) are ligand-activated transcription
factors that mainly regulate genes responsible for fatty acid (FA) and energy metabolism …
factors that mainly regulate genes responsible for fatty acid (FA) and energy metabolism …
PPARs as therapeutic targets in cardiovascular disease
M van Bilsen, FA van Nieuwenhoven - Expert opinion on …, 2010 - Taylor & Francis
Importance of the field: The role of peroxisome proliferator-activated receptors PPARα,
PPARδ and PPARγ in cardiovascular disease is receiving widespread attention. As ligand …
PPARδ and PPARγ in cardiovascular disease is receiving widespread attention. As ligand …
PPARs: regulators of metabolism and as therapeutic targets in cardiovascular disease. Part II: PPAR-β/δ and PPAR-γ
The PPARs are a subfamily of three ligand-inducible transcription factors, which belong to
the superfamily of nuclear hormone receptors. In mammals, the PPAR subfamily consists of …
the superfamily of nuclear hormone receptors. In mammals, the PPAR subfamily consists of …
PPAR ligands: are they potential agents for cardiovascular disorders?
P Balakumar, M Rose, M Singh - Pharmacology, 2007 - karger.com
Peroxisome proliferator activated receptors (PPARs) are members of the nuclear hormone
receptor superfamily of ligand-activated transcription factors. The PPAR subfamily consists …
receptor superfamily of ligand-activated transcription factors. The PPAR subfamily consists …
The peroxisome proliferator‐activated receptors in cardiovascular diseases: experimental benefits and clinical challenges
The peroxisome proliferator‐activated receptors, PPAR α, PPAR β/δ and PPAR γ, are ligand‐
activated transcriptional factors belonging to the nuclear receptors superfamily and they are …
activated transcriptional factors belonging to the nuclear receptors superfamily and they are …
Update on cardiovascular safety of PPARgamma agonists and relevance to medicinal chemistry and clinical pharmacology
A Ciudin, C Hernandez, R Simo - Current topics in medicinal …, 2012 - ingentaconnect.com
Peroxisome proliferator-activator receptors (PPARs) are now known as members of the
nuclear hormonereceptor superfamily of ligand-activated transcription factors that regulate …
nuclear hormonereceptor superfamily of ligand-activated transcription factors that regulate …
Safety issues and prospects for future generations of PPAR modulators
A Rubenstrunk, R Hanf, DW Hum, JC Fruchart… - … et Biophysica Acta (BBA …, 2007 - Elsevier
Because of their wide range of actions on glucose homeostasis, lipid metabolism and
vascular inflammation, peroxisome proliferator-activated receptors (PPARs) are promising …
vascular inflammation, peroxisome proliferator-activated receptors (PPARs) are promising …
PPARs as targets for metabolic and cardiovascular diseases
PTW Cheng, R Mukherjee - Mini reviews in medicinal …, 2005 - ingentaconnect.com
Peroxisome proliferator-activated receptors (PPARs) alpha, gamma and delta (beta) are
ligandactivated transcription factors of the nuclear hormone receptor superfamily which have …
ligandactivated transcription factors of the nuclear hormone receptor superfamily which have …
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