Modulation of Hepatic Inflammatory Risk Markers of Cardiovascular Diseases by PPAR–α Activators: Clinical and Experimental Evidence
A Zambon, P Gervois, P Pauletto… - … and Vascular Biology, 2006 - Am Heart Assoc
Atherosclerosis is a long-term chronic inflammatory disease associated with increased
concentrations of inflammatory hepatic markers, such as CRP and fibrinogen, and of …
concentrations of inflammatory hepatic markers, such as CRP and fibrinogen, and of …
Peroxisome proliterator-activated receptor-alpha activators regulate genes governing lipoprotein metabolism, vascular inflammation and atherosclerosis
JC Fruchart, P Duriez, B Staels - Current opinion in lipidology, 1999 - journals.lww.com
The peroxisome proliferator-activated receptors (PPARs)[alpha, delta (beta) and gamma]
form a subfamily of the nuclear receptor gene family. All PPARs are, albeit to different …
form a subfamily of the nuclear receptor gene family. All PPARs are, albeit to different …
Peroxisome proliferator-activated receptor-alpha and atherosclerosis: from basic mechanisms to clinical implications
Z Israelian-Konaraki, PD Reaven - Cardiology, 2004 - karger.com
Atherosclerosis is an inflammatory process triggered by the presence of lipids in the
vascular wall and encompasses a complex interaction between inflammatory cells, vascular …
vascular wall and encompasses a complex interaction between inflammatory cells, vascular …
Peroxisome proliferator-activated receptors and inflammation: from basic science to clinical applications
G Chinetti, JC Fruchart, B Staels - International Journal of Obesity, 2003 - nature.com
Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear receptor
family. After activation by specific ligands, they regulate the transcription of genes involved in …
family. After activation by specific ligands, they regulate the transcription of genes involved in …
Role of Peroxisome Proliferator‐Activated Receptor‐γ in Vascular Inflammation
K Ohshima, M Mogi, M Horiuchi - International journal of …, 2012 - Wiley Online Library
Vascular inflammation plays a crucial role in atherosclerosis, and its regulation is important
to prevent cerebrovascular and coronary artery disease. The inflammatory process in …
to prevent cerebrovascular and coronary artery disease. The inflammatory process in …
Peroxisome proliferator-activated receptor (PPAR)-α: a pharmacological target with a promising future
DH van Raalte, M Li, PH Pritchard, KM Wasan - Pharmaceutical research, 2004 - Springer
Peroxisome proliferator-activated receptor (PPAR)-α is a ligand-activated transcriptional
factor that belongs to the family of nuclear receptors. PPAR-α regulates the expression of …
factor that belongs to the family of nuclear receptors. PPAR-α regulates the expression of …
PPARα in atherosclerosis and inflammation
F Zandbergen, J Plutzky - Biochimica et Biophysica Acta (BBA)-Molecular …, 2007 - Elsevier
Peroxisome proliferator-activated receptor (PPAR) α is a nuclear receptor activated by
natural ligands such as fatty acids as well as by synthetic ligands such as fibrates currently …
natural ligands such as fatty acids as well as by synthetic ligands such as fibrates currently …
Modulation of vascular inflammation by PPARs.
DM Tham, YX Wang, JC Rutledge - Drug News & Perspectives, 2003 - europepmc.org
The activation of cells in atherosclerotic lesions leads to the release of proinflammatory
molecules and the onset of a chronic inflammatory response. Recent evidence suggests that …
molecules and the onset of a chronic inflammatory response. Recent evidence suggests that …
Peroxisome proliferator-activated receptors in atherosclerosis and inflammation—an update
CS Elangbam, RD Tyler… - Toxicologic pathology, 2001 - journals.sagepub.com
Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear receptor
subfamily of transcription factors with pleiotropic effects on intra-and extracellular lipid …
subfamily of transcription factors with pleiotropic effects on intra-and extracellular lipid …
Peroxisome proliferator-activated receptor α in lipid metabolism and atherosclerosis
XH Yu, XL Zheng, CK Tang - Advances in clinical chemistry, 2015 - Elsevier
Atherosclerosis is a chronic inflammatory disease with deposition of excessive cholesterol in
the arterial intima. Peroxisome proliferator-activated receptor α (PPARα) is a nuclear …
the arterial intima. Peroxisome proliferator-activated receptor α (PPARα) is a nuclear …