[HTML][HTML] Deuterium in drug discovery: progress, opportunities and challenges

RMC Di Martino, BD Maxwell, T Pirali - Nature Reviews Drug Discovery, 2023 - nature.com
Substitution of a hydrogen atom with its heavy isotope deuterium entails the addition of one
neutron to a molecule. Despite being a subtle change, this structural modification, known as …

Deuterium in drug discovery: progress, opportunities and challenges.

RMC Di Martino, BD Maxwell, T Pirali - Nature reviews. Drug …, 2023 - europepmc.org
Substitution of a hydrogen atom with its heavy isotope deuterium entails the addition of one
neutron to a molecule. Despite being a subtle change, this structural modification, known as …

[HTML][HTML] Deuterium in drug discovery: progress, opportunities and challenges

RMC Di Martino, BD Maxwell, T Pirali - Nature Reviews. Drug Discovery - ncbi.nlm.nih.gov
Substitution of a hydrogen atom with its heavy isotope deuterium entails the addition of one
neutron to a molecule. Despite being a subtle change, this structural modification, known as …

Deuterium in drug discovery: progress, opportunities and challenges

RMC Di Martino, BD Maxwell… - Nature reviews. Drug …, 2023 - pubmed.ncbi.nlm.nih.gov
Substitution of a hydrogen atom with its heavy isotope deuterium entails the addition of one
neutron to a molecule. Despite being a subtle change, this structural modification, known as …

Deuterium in drug discovery: progress, opportunities and challenges

RMC Di Martino, BD Maxwell, T Pirali - NATURE REVIEWS DRUG …, 2023 - iris.uniupo.it
Substituting a hydrogen atom with its heavy isotope deuterium may improve the
pharmacokinetic and/or toxicity profile of a drug compared with its non-deuterated …

Deuterium in drug discovery: progress, opportunities and challenges

RMC DI MARTINO, BD Maxwell… - Nature Reviews Drug …, 2023 - research.uniupo.it
Substituting a hydrogen atom with its heavy isotope deuterium may improve the
pharmacokinetic and/or toxicity profile of a drug compared with its non-deuterated …

Deuterium in drug discovery: progress, opportunities and challenges.

RMC Di Martino, BD Maxwell, T Pirali - Nature reviews. Drug …, 2023 - europepmc.org
Substitution of a hydrogen atom with its heavy isotope deuterium entails the addition of one
neutron to a molecule. Despite being a subtle change, this structural modification, known as …

Deuterium in drug discovery: progress, opportunities and challenges

RMC DI MARTINO, BD Maxwell… - Nature Reviews Drug …, 2023 - research.uniupo.it
Substituting a hydrogen atom with its heavy isotope deuterium may improve the
pharmacokinetic and/or toxicity profile of a drug compared with its non-deuterated …