Redox control of calcium channels: from mechanisms to therapeutic opportunities
… affinity (pore binding dissociation constant 2 nM) and biophysical characteristics that included
an inwardly rectifying current suited to calcium uptake into mitochondria and inhibition by …
an inwardly rectifying current suited to calcium uptake into mitochondria and inhibition by …
Redox control of mitochondrial calcium uptake
N Demaurex, M Rosselin - Molecular cell, 2017 - cell.com
… + uptake to the cellular redox state. … uptake at physiological cytosolic Ca2+ levels, with
deleterious consequences on mitochondrial bioenergetics and cellular function. The redox control …
deleterious consequences on mitochondrial bioenergetics and cellular function. The redox control …
Redox stability controls the cellular uptake and activity of ruthenium‐based inhibitors of the mitochondrial calcium uniporter (MCU)
… tested the mitochondrial calcium uptake inhibition properties of … Our evaluation of mitochondrial
calcium uptake inhibition … and the Ca 2+ -responsive fluorescent dye Calcium Green-5 n …
calcium uptake inhibition … and the Ca 2+ -responsive fluorescent dye Calcium Green-5 n …
Mitochondrial calcium regulation of redox signaling in cancer
C Delierneux, S Kouba, S Shanmughapriya… - Cells, 2020 - mdpi.com
… Calcium (Ca 2+ ) uptake into the mitochondrial matrix from the cytoplasm occurs at the …
One of the major signaling mechanisms that control [Ca 2+ ]m dynamics is store-operated Ca 2+ …
One of the major signaling mechanisms that control [Ca 2+ ]m dynamics is store-operated Ca 2+ …
Redox regulation of cardiac calcium channels and transporters
AV Zima, LA Blatter - Cardiovascular research, 2006 - academic.oup.com
… The redox status of the intracellular milieu is controlled by a variety of … Furthermore, ROS
cause inhibition of SERCA function by uncoupling Ca 2+ uptake activity from ATP hydrolysis [5]. …
cause inhibition of SERCA function by uncoupling Ca 2+ uptake activity from ATP hydrolysis [5]. …
Redox regulation of calcium ion channels: chemical and physiological aspects
… of redox regulation of Ca 2+ permeable ion channels such as voltage-gated (CaV) Ca 2+
channels… 2+ ] o ), already indicates the importance of constant and tight control of cellular Ca 2+ …
channels… 2+ ] o ), already indicates the importance of constant and tight control of cellular Ca 2+ …
Redox active calcium ion channels and cell death
P Waring - Archives of biochemistry and biophysics, 2005 - Elsevier
… review is on calcium channels. The reader interested in redox controlled ion channels per …
transients induced by activation of IP 3 sensitive channels in the ER cause uptake of calcium …
transients induced by activation of IP 3 sensitive channels in the ER cause uptake of calcium …
Redox Regulation of Store-Operated Ca2+ Entry
P Nunes, N Demaurex - Antioxidants & redox signaling, 2014 - liebertpub.com
… set of SOCE controlling molecules, to determine their redox-… consequence of key redox-sensitive
components of the pre- … The effects of thimerosal on calcium uptake and inositol 1,4,5…
components of the pre- … The effects of thimerosal on calcium uptake and inositol 1,4,5…
Redox modulation of cellular signaling and metabolism through reversible oxidation of methionine sensors in calcium regulatory proteins
DJ Bigelow, TC Squier - Biochimica et Biophysica Acta (BBA)-Proteins and …, 2005 - Elsevier
… The essential role of the Ca-ATPase in controlling properties of the calcium transient suggests
its possible role as an additional sensor of oxidative stress working in concert with CaM in …
its possible role as an additional sensor of oxidative stress working in concert with CaM in …
Redox nanodomains are induced by and control calcium signaling at the ER-mitochondrial interface
… Ca 2+ in shaping the interface redox environment, we stimulated cells with an IP 3 -linked
agonist and a SERCA inhibitor, thapsigargin (Tg), to elicit ER Ca 2… mitochondrial Ca 2+ uptake, …
agonist and a SERCA inhibitor, thapsigargin (Tg), to elicit ER Ca 2… mitochondrial Ca 2+ uptake, …
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