[HTML][HTML] Anti-trypanosomatid drug discovery: progress and challenges
… to facilitate studies of drug mechanisms of action… progress in drug discovery for kinetoplastid
diseases and how an improved understanding of parasite biology affects the drug discovery …
diseases and how an improved understanding of parasite biology affects the drug discovery …
Alchemical free energy methods for drug discovery: progress and challenges
… , we discuss a number of challenges that remain before these approaches can provide clear
utility in industrial drug discovery challenges where existing virtual screening approaches …
utility in industrial drug discovery challenges where existing virtual screening approaches …
[PDF][PDF] Challenges in drug discovery: can we improve drug development
B Arun - Journal of Bioanalysis & Biomedicine, 2009 - hal.science
… This clearly points out that the various advancements in early drug discovery has increased
the pipeline … These approaches will probably improve our current lacunae in drug discovery. …
the pipeline … These approaches will probably improve our current lacunae in drug discovery. …
Drug repositioning: Progress and challenges in drug discovery for various diseases
Y Hua, X Dai, Y Xu, G Xing, H Liu, T Lu, Y Chen… - European Journal of …, 2022 - Elsevier
Compared with traditional de novo drug discovery, drug repurposing has become an attractive
drug discovery strategy due to its low-cost and high efficiency. Through a comprehensive …
drug discovery strategy due to its low-cost and high efficiency. Through a comprehensive …
Challenges for drug discovery and development in China
KL Hon, VWY Lee - Expert Opinion on Drug Discovery, 2017 - Taylor & Francis
… This overview summarize the challenges in drug discovery in China in anticancer,
antiallergy, anti-infectious, and pCM for various chronic diseases (such as the allergic diseases …
antiallergy, anti-infectious, and pCM for various chronic diseases (such as the allergic diseases …
Current and future challenges in modern drug discovery
CS Tautermann - Quantum mechanics in drug discovery, 2020 - Springer
… , the drug discovery business looks … challenges in drug discovery. Because this article is
part of a book on quantum mechanics (QM) in drug design, I will clearly focus on the discovery of …
part of a book on quantum mechanics (QM) in drug design, I will clearly focus on the discovery of …
Leishmaniasis drug discovery: recent progress and challenges in assay development
… for compound progression within the drug discovery pipeline have been determined as
the minimal requirements for the development of a safe, oral, effective anti-leishmanial drug, …
the minimal requirements for the development of a safe, oral, effective anti-leishmanial drug, …
Progress and challenges in the discovery of macrofilaricidal drugs
TG Geary, CD Mackenzie - Expert review of anti-infective therapy, 2011 - Taylor & Francis
… drug discovery pipelines are poorly populated and the process of macrofilaricide discovery
and development remains highly challenging… drug discovery pathway is an unresolved issue. …
and development remains highly challenging… drug discovery pathway is an unresolved issue. …
Drug development and discovery: challenges and opportunities
M Moridani, S Harirforoosh - Drug discovery today, 2014 - Elsevier
… of drug development and discovery, the current communication discusses only the challenges
… companies and academic scientists over the course of drug discovery and development. …
… companies and academic scientists over the course of drug discovery and development. …
[HTML][HTML] Deuterium in drug discovery: progress, opportunities and challenges
RMC Di Martino, BD Maxwell, T Pirali - Nature Reviews Drug Discovery, 2023 - nature.com
… drug deucravacitinib in 2022. In this Review, we highlight key milestones in the field of
deuteration in drug discovery … the opportunities and hurdles for drug developers, as well as the …
deuteration in drug discovery … the opportunities and hurdles for drug developers, as well as the …
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