… A key characteristic of Human immunodeficiency virus type 1 (HIV-1) infection is the … type-I
interferons (type I IFN) and IFN-stimulated genes (ISGs). The balance in the IFN signaling and …

… underlying HIV-1 dysregulation of the IFNγ signaling system, we examined whether HIV-1
Tat acts through the induction of SOCS family of proteins to suppress IFNγ activation of Jak/…

… HIV-1-positive individuals with low IFN-γ responses We hypothesized that IFN-γ responses
in chronic HIV-1-… We compared the frequencies of cells secreting IFN-γ and IL-4, alone or …

… the pro-inflammatory cytokines IFN-γ and TNF-α, in conjunction with HIV-1 Tat, all of which
… that the combined actions of HIV-1 Tat and the pro-inflammatory cytokines, IFN-γ and TNF-α…

… of T H 1 and T H 2 cytokines by HIV-infected children who have suppressed HIV replication.
… , CD4 + T cells were enumerated, plasma HIV-1 RNA was measured, and levels of cytokine …

… -specific CD8 T-cell responses commensurate with falling plasma HIV-1 RNA concentration
… HIV p24 antigen detection and preceding HIV-1 antibody seroconversion. Studies of HIV-1 …

… interferons (IFNs)—in response to viruses. Their natural IFN production is impaired in chronic
HIV … MethodsWe longitudinally studied 26 patients during the primary stage of HIV infection…

… on 948 HIV-1-infected patients, subjects with an indeterminate IFN-γ (gamma interferon)
release … Thus, in HIV-1-infected patients with advanced quantitative CD4 + T cell depletion, an …

… regulation of IFN-λ during HIV-1 infection, we also quantified the production of type I IFNs
(IFN-α, -β, and -ω), type II IFN (IFN-γ), and IL-10 in the plasma of HIV-1 infected individuals, …

… between early HIV-1-specific IFN-γ responses and outcomes of HIV-1 infection … HIV-1 RNA
plasma viral replication over time in infants with or without HIV-1-specific IFN-γ responses at 1 …