Development and validation of an ultra-high performance liquid chromatography–tandem mass spectrometry method to measure creatinine in human urine

S Fraselle, K De Cremer, W Coucke, G Glorieux… - … of Chromatography B, 2015 - Elsevier
… in urine. In this paper, the development and validation of a very simple and robust method
requiring a limited urine sample volume and no purification step is described. All obtained …

Development and validation of an open screening method for diuretics, stimulants and selected compounds in human urine by UHPLC–HRMS for doping control

AJ Girón, K Deventer, K Roels, P Van Eenoo - Analytica Chimica Acta, 2012 - Elsevier
… screening in human urine doping control. In the present work, a new and rapid screening
method has been developed and validated for the analysis of 122 target analytes in urine by …

[HTML][HTML] Development and validation of LC-Q-TOF-MS methodology to determine mycotoxin biomarkers in human urine

N Dasí-Navarro, M Lozano, S Llop, A Esplugues… - Toxins, 2022 - mdpi.com
human exposure to mycotoxins is a key concern. Most mycotoxins and their metabolites are
excreted in urine, but … The aim of this work is to validate a sensitive methodology capable of …

Development and validation of an HPLC method for the simultaneous analysis of 23 selected drugs belonging to different therapeutic groups in human urine samples

I Baranowska, P Markowski, J Baranowski - Analytical sciences, 2009 - jstage.jst.go.jp
… In this study we developed a simple and reliable procedure for the determination of ENA,
PAR, SOT, DIP, VAN, CAP, FLU, CEF, MET, ASP, TIC, PRE, PRO, DIG, SIL, FUR, DEX, CAR, …

Development and validation of a simple high performance liquid chromatography/UV method for simultaneous determination of urinary uric acid, hypoxanthine, and …

N Wijemanne, P Soysa, S Wijesundara… - … journal of analytical …, 2018 - Wiley Online Library
… (HPLC/UV) technique, developed and validated for simultaneous analysis of uric acid,
hypoxanthine, and creatinine in human urine. Urine was diluted appropriately and eluted with C‐…

[HTML][HTML] Development and validation of an ultra-performance liquid chromatography quadrupole time of flight mass spectrometry method for rapid quantification of free …

R Joyce, V Kuziene, X Zou, X Wang, F Pullen, RL Loo - Amino Acids, 2016 - Springer
… This study aimed at the development and validation of a UPLC-qTOF-MS method using … of
free amino acids in human urine samples. We assessed the optimal urine sample preparation …

Fast gas chromatographic/mass spectrometric determination of diuretics and masking agents in human urine: Development and validation of a productive screening …

V Morra, P Davit, P Capra, M Vincenti, A Di Stilo… - … of Chromatography A, 2006 - Elsevier
… a masking agent (probenecid) in human urine. The whole method involves three analytical
… The analytical method was validated by determining selectivity, linearity, accuracy, intra and …

Measurement of human growth hormone in urine: development and validation of a sensitive and specific assay

P Hourd, R Edwards - Journal of endocrinology, 1989 - joe.bioscientifica.com
… We have reported the development and validation ofa sensitive and specific IRMA for the
direct measure¬ ment of hGH in urine. It became apparent during this study that precise …

Development and validation of LC–MS/MS methods for the determination of EVT201 and its five metabolites in human urine: Application to a mass balance study

M Liu, X Wang, D Zhang, L Zhang, C Pan… - Journal of Chromatography …, 2023 - Elsevier
… in human urine has been reported. In this article, we present the development and validation
… and its metabolites in human urine, the methods have been validated based on the NMPA …

Development and validation of a gas chromatography–mass spectrometry method for determination of deoxynivalenol and its metabolites in human urine

SC Cunha, JO Fernandes - Food and chemical toxicology, 2012 - Elsevier
… includes simple validated GC–MS method for determination of DON and its metabolites in
human urine. ► DON and its metabolites can be extracted by SPE C18 from human urine. ► …