Immune signatures for HIV-1 and HIV-2 induced CD4+T cell dysregulation in an Indian cohort

S Salwe, A Singh, V Padwal, S Velhal, V Nagar… - BMC infectious …, 2019 - Springer
… progression than HIV-1 infection. Identifying unique immune signatures associated with
HIV-2 pathogenesis may thus provide therapeutically useful insight into the management of HIV

Innate immune signatures to a partially-efficacious HIV vaccine predict correlates of HIV-1 infection risk

E Andersen-Nissen, A Fiore-Gartland… - PLoS …, 2021 - journals.plos.org
… Although we have not yet performed a formal comparison between the innate immune
response to MRKAd5-HIV and ALVAC-HIV in the present study, the dominant response signature

[HTML][HTML] Molecular immune signatures of HIV-1 vaccines in human PBMCs

A Monaco, FM Marincola, M Sabatino, Z Pos… - FEBS letters, 2009 - Elsevier
… , VLPs) has been evaluated in HIV-infected patients with low/high … HIV-infected patients
and innate immune stimulation with HIV-VLPs was not blunted. The immune profile among HIV-…

A plasma biomarker signature of immune activation in HIV patients on antiretroviral therapy

A Kamat, V Misra, E Cassol, P Ancuta, Z Yan, C Li… - PloS one, 2012 - journals.plos.org
… These findings identify CXCL10 as a component of the plasma inflammatory biomarker
signature we identified in HIV subjects that is strongly associated with disease markers (high …

[HTML][HTML] Phenotypic signatures of immune selection in HIV-1 reservoir cells

W Sun, C Gao, CA Hartana, MR Osborn, KB Einkauf… - Nature, 2023 - nature.com
… to intensify and accelerate immune selection of HIV-1 reservoir cells may be of benefit for
reducing HIV-1 long-term persistence and inducing a drug-free remission of HIV-1 infection. …

Correlating cellular and molecular signatures of mucosal immunity that distinguish HIV controllers from noncontrollers

P Loke, D Favre, PW Hunt, JM Leung… - Blood, The Journal …, 2010 - ashpublications.org
… segregated the HIV controllers and noncontrollers into 2 distinct groups based on their
immune and clinical parameters (Figure 2A). High expression of immune activation markers (Ki67 …

Plasma microRNA signature panel predicts the immune response after antiretroviral therapy in HIV-infected patients

JN Lv, JQ Li, YB Cui, YY Ren, YJ Fu, YJ Jiang… - Frontiers in …, 2021 - frontiersin.org
… the level of immune reconstitution in INRs (4). In the current study, we aimed to develop a
practical and effective predictor of immune responses in people with HIV receiving ART. …

Molecular signatures of T-cell inhibition in HIV-1 infection

M Larsson, EM Shankar, KF Che, A Saeidi, R Ellegård… - Retrovirology, 2013 - Springer
… of immune inhibition is likely to contribute to development of therapeutic interventions that
augment the functionality of host immune cells leading to improved immune control of HIVHIV

Gene expression signatures associated with immune and virological responses to therapeutic vaccination with dendritic cells in HIV-infected individuals

R Thiébaut, BP Hejblum, H Hocini… - Frontiers in …, 2019 - frontiersin.org
HIV-lipopeptides in HIV-infected patients (n = 19) on antiretroviral therapy (ART) was well-tolerated
and immunogenic. Vaccine-elicited HIVHIV-specific responses (production of IL-2, IL-…

A vaccine-induced gene expression signature correlates with protection against SIV and HIV in multiple trials

PK Ehrenberg, S Shangguan, B Issac, G Alter… - Science translational …, 2019 - science.org
… individual immune response for enrichment of the B cell gene signature, we observed that
it associated with higher antibody-dependent cellular phagocytosis (ADCP), percent tier 2