Immune signatures for HIV-1 and HIV-2 induced CD4+T cell dysregulation in an Indian cohort
S Salwe, A Singh, V Padwal, S Velhal, V Nagar… - BMC infectious …, 2019 - Springer
… progression than HIV-1 infection. Identifying unique immune signatures associated with
HIV-2 pathogenesis may thus provide therapeutically useful insight into the management of HIV …
HIV-2 pathogenesis may thus provide therapeutically useful insight into the management of HIV …
Innate immune signatures to a partially-efficacious HIV vaccine predict correlates of HIV-1 infection risk
E Andersen-Nissen, A Fiore-Gartland… - PLoS …, 2021 - journals.plos.org
… Although we have not yet performed a formal comparison between the innate immune
response to MRKAd5-HIV and ALVAC-HIV in the present study, the dominant response signature …
response to MRKAd5-HIV and ALVAC-HIV in the present study, the dominant response signature …
[HTML][HTML] Molecular immune signatures of HIV-1 vaccines in human PBMCs
… , VLPs) has been evaluated in HIV-infected patients with low/high … HIV-infected patients
and innate immune stimulation with HIV-VLPs was not blunted. The immune profile among HIV-…
and innate immune stimulation with HIV-VLPs was not blunted. The immune profile among HIV-…
A plasma biomarker signature of immune activation in HIV patients on antiretroviral therapy
… These findings identify CXCL10 as a component of the plasma inflammatory biomarker
signature we identified in HIV subjects that is strongly associated with disease markers (high …
signature we identified in HIV subjects that is strongly associated with disease markers (high …
[HTML][HTML] Phenotypic signatures of immune selection in HIV-1 reservoir cells
… to intensify and accelerate immune selection of HIV-1 reservoir cells may be of benefit for
reducing HIV-1 long-term persistence and inducing a drug-free remission of HIV-1 infection. …
reducing HIV-1 long-term persistence and inducing a drug-free remission of HIV-1 infection. …
Correlating cellular and molecular signatures of mucosal immunity that distinguish HIV controllers from noncontrollers
… segregated the HIV controllers and noncontrollers into 2 distinct groups based on their
immune and clinical parameters (Figure 2A). High expression of immune activation markers (Ki67 …
immune and clinical parameters (Figure 2A). High expression of immune activation markers (Ki67 …
Plasma microRNA signature panel predicts the immune response after antiretroviral therapy in HIV-infected patients
JN Lv, JQ Li, YB Cui, YY Ren, YJ Fu, YJ Jiang… - Frontiers in …, 2021 - frontiersin.org
… the level of immune reconstitution in INRs (4). In the current study, we aimed to develop a
practical and effective predictor of immune responses in people with HIV receiving ART. …
practical and effective predictor of immune responses in people with HIV receiving ART. …
Molecular signatures of T-cell inhibition in HIV-1 infection
… of immune inhibition is likely to contribute to development of therapeutic interventions that
augment the functionality of host immune cells leading to improved immune control of HIV … HIV …
augment the functionality of host immune cells leading to improved immune control of HIV … HIV …
Gene expression signatures associated with immune and virological responses to therapeutic vaccination with dendritic cells in HIV-infected individuals
R Thiébaut, BP Hejblum, H Hocini… - Frontiers in …, 2019 - frontiersin.org
… HIV-lipopeptides in HIV-infected patients (n = 19) on antiretroviral therapy (ART) was well-tolerated
and immunogenic. Vaccine-elicited HIV… HIV-specific responses (production of IL-2, IL-…
and immunogenic. Vaccine-elicited HIV… HIV-specific responses (production of IL-2, IL-…
A vaccine-induced gene expression signature correlates with protection against SIV and HIV in multiple trials
PK Ehrenberg, S Shangguan, B Issac, G Alter… - Science translational …, 2019 - science.org
… individual immune response for enrichment of the B cell gene signature, we observed that
it associated with higher antibody-dependent cellular phagocytosis (ADCP), percent tier 2 …
it associated with higher antibody-dependent cellular phagocytosis (ADCP), percent tier 2 …
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