Intermediate-risk prostate cancer: stratification and management

F Preisser, MR Cooperberg, J Crook, F Feng… - European Urology …, 2020 - Elsevier
… of ADT in addition to radiotherapy in intermediate-risk prostate cancer patients, included a
small … from the HYPO-RT-PC (HYPOfractionated RadioTherapy of intermediate risk localised …

Androgen deprivation therapy and the risk of death from prostate cancer among men with favorable or unfavorable intermediaterisk disease

FK Keane, MH Chen, D Zhang, BJ Moran… - Cancer, 2015 - Wiley Online Library
… with intermediate-risk PC receiving RT with 4 to 6 months of ADT compared with RT alone,7-10
these trials used RT … These higher RT doses were established based on 2 RCTs that …

Long-term outcomes of stereotactic body radiotherapy for low-risk and intermediate-risk prostate cancer

AU Kishan, A Dang, AJ Katz, CA Mantz… - JAMA network …, 2019 - jamanetwork.com
… The preliminary results of the HYPO-RT-PC trial, which compared 78 Gy in 39 fractions with
… follow-up than in the HYPO-RT-PC study and also presents outcomes after more typical …

Is androgen deprivation therapy necessary in all intermediate-risk prostate cancer patients treated in the dose escalation era?

KO Castle, KE Hoffman, LB Levy, AK Lee… - International Journal of …, 2013 - Elsevier
… radiation therapy (RT) for men with intermediate-risk prostate cancer is unclear; therefore,
we assessed the impact of adding ADT to dose-escalated RT on freedom from failure (FFF). …

A new risk classification system for therapeutic decision making with intermediate-risk prostate cancer patients undergoing dose-escalated external-beam radiation …

ZS Zumsteg, DE Spratt, I Pei, Z Zhang, Y Yamada… - European urology, 2013 - Elsevier
prostate-… intermediate risk (FIR) or unfavorable intermediate risk (UIR). Given that
androgen-deprivation therapy (ADT) has been shown to improve survival in high- but not low-risk

The likelihood of death from prostate cancer in men with favorable or unfavorable intermediaterisk disease

FK Keane, MH Chen, D Zhang, MJ Loffredo… - Cancer, 2014 - Wiley Online Library
… Reference groups for categorical variables were defined as treatment with RT and AST,
unfavorable intermediate-risk PC, and a comorbidity score of 0 (none) or 1 (minimal). To account …

… conventionally fractionated radiotherapy for intermediate risk prostate cancer: early toxicity results from the Scandinavian randomized phase III trial “HYPO-RT-PC

A Widmark, A Gunnlaugsson, L Beckman… - International Journal of …, 2016 - redjournal.org
Prostate cancer is postulated to have high radiation-fractionation sensitivity, which suggests
a … The HYPO-RT-PC non-inferiority trial accrued 1200 intermediate risk prostate cancer

Role of combined radiation and androgen deprivation therapy in intermediate-risk prostate cancer: Statement from the DEGRO working group on prostate cancer

…, Prostate Cancer Expert Panel of the German … - Strahlentherapie und …, 2020 - Springer
… On the basis of a subdivision of the intermediate-risk PC group, an … RT in case of favorable
intermediate-risk PC and combination of RT and ADT in unfavorable intermediate-risk PC

Short-term androgen-deprivation therapy improves prostate cancer-specific mortality in intermediate-risk prostate cancer patients undergoing dose-escalated external …

ZS Zumsteg, DE Spratt, X Pei, Y Yamada… - International Journal of …, 2013 - Elsevier
… In contrast, a preliminary report from a prospective randomized trial enrolling patients
with intermediate-risk PC treated with dose-escalated RT showed that the addition of short-term …

Impact of the percentage of positive prostate cores on prostate cancer–specific mortality for patients with low or favorable intermediate-risk disease

AV D'Amico, AA Renshaw, K Cote, M Hurwitz… - Journal of Clinical …, 2004 - ascopubs.org
PC predicted time to PCSM after CRT for patients with low- or favorable intermediate-risk
prostate cancer. … time to PSA failure after RP or RT for the % PC using a breakpoint of 50%, 3,4 …