[HTML][HTML] Sensitization of TRPV1 by protein kinase C in rats with mono-iodoacetate-induced joint pain

K Koda, K Hyakkoku, K Ogawa, K Takasu, S Imai… - Osteoarthritis and …, 2016 - Elsevier
pain. We investigated the functional change of TRPV1 in OA pain using a mono-iodoacetate
(MIA) induced joint pain … resulting in joint degeneration and cartilage loss with joint pain in …

Osteoarthritis pain model induced by intra-articular injection of mono-iodoacetate in rats

J Xu, L Yan, B Yan, L Zhou, P Tong, L Shan - JoVE (Journal of Visualized …, 2020 - jove.com
… MIA model may be useful for investigating chronic nociceptive pain 10 , 11 , 12 . In this study…
MIA in the knee joints. The severity of MIA-induced joint pain was measured by assessment …

Monoiodoacetate‐induced experimental osteoarthritis. A dose‐response study of loss of mobility, morphology, and biochemistry

C Guingamp, P Gegout‐Pottie… - … : Official Journal of …, 1997 - Wiley Online Library
… in patellar cartilage, as measured by Na,”S04 incorporation after intraarticular injection of
various doses of mono-iodoacetate (MIA) in the right knee joint of rats. A, 3.0 mg. B, 0.3 mg. …

Monosodium iodoacetate-induced joint pain is associated with increased phosphorylation of mitogen activated protein kinases in the rat spinal cord

Y Lee, M Pai, JD Brederson, D Wilcox… - … pain, 2011 - journals.sagepub.com
… Intra-articular injection of monosodium iodoacetate (MIA) in the knee joint of rats disrupts …
as a model of osteoarthritis (OA) pain. Central sensitization through activation of mitogen …

The pharmacology of pain associated with the monoiodoacetate model of osteoarthritis

J de Sousa Valente - Frontiers in pharmacology, 2019 - frontiersin.org
… It is defined clinically by joint pain, deformity, and loss of function and pathologically by …
Figure 1 Histopathological progression in the monosodium iodoacetate model of osteoarthritis. …

Role of CB1 and CB2 cannabinoid receptors in the development of joint pain induced by monosodium iodoacetate

C La Porta, SA Bura, A Aracil-Fernández… - PAIN®, 2013 - Elsevier
… is a common clinical problem for which both inflammatory and degenerative joint diseases …
joint pain. The murine model of monosodium iodoacetate (MIA) was used to induce joint pain

Pain Intensity and Trajectory Following Intra-Articular Injection of Mono-Iodoacetate in Experimental Osteoarthritis: A Meta-Analysis of In Vivo Studies

H Jin, Y Yang, G Lei, C Zeng, K He, Y Wang… - Cartilage, 2023 - journals.sagepub.com
… (OA) pain induction, intra-articular mono-iodoacetate (MIA) injection … Herein, we aimed to
compare the pain intensity of rats … the development of pain behaviour and joint pathology in a …

[HTML][HTML] Monosodium iodoacetate-induced monoarthritis develops differently in knee versus ankle joint in rats

KÄ Möller, S Klein, F Seeliger, A Finn, C Stenfors… - Neurobiology of Pain, 2019 - Elsevier
pain are major symptoms of joint disease, motivating the development of methods to quantify
motor behaviour in rodent joint pain … evaluation after induction of rat monoiodoacetate (MIA) …

Intra-articular injection of mono-iodoacetate induces osteoarthritis of the hip in rats

S Miyamoto, J Nakamura, S Ohtori, S Orita… - BMC musculoskeletal …, 2016 - Springer
… of pain and joint destruction. OA is characterized by a progressive degeneration of articular
cartilage [4, 5]. Increases of mechanical stress and biochemical factors in the affected joints

[图书][B] The monosodium iodoacetate-induced model of osteoarthritis pain: Behaviour, pharmacological, immunohistochemical and electrophysiological studies

JLR Vonsy - 2008 - search.proquest.com
… Osteoarthritis (OA), a chronic degenerative joint disease, will affect an increasing number of
… knee osteoarthritis pain induced by intra-articular injection of monosodium iodoacetate, an …