Imiquimod‐induced apoptosis of melanoma cells is mediated by ER stress‐dependent Noxa induction and enhanced by NF‐κB inhibition
A El‐Khattouti, D Selimovic, M Hannig… - Journal of cellular …, 2016 - Wiley Online Library
… NF-κB pathway To investigate if the inhibition of ER stress influences imiquimod-induced
cytotoxic effects in melanoma cells, we next pre-treated melanoma cell … imiquimod, cells were …
cytotoxic effects in melanoma cells, we next pre-treated melanoma cell … imiquimod, cells were …
NF-κB in the vascular progression of melanoma
M Kashani-Sabet, L Shaikh, JR Miller III… - Journal of clinical …, 2004 - ascopubs.org
… To our knowledge, however, this is the first study to suggest the impact of NF-κB on
melanoma cell invasiveness, and on the development of vascular factors, directly in human …
melanoma cell invasiveness, and on the development of vascular factors, directly in human …
Antioxidants tiron and N-acetyl-L-cysteine differentially mediate apoptosis in melanoma cells via a reactive oxygen species-independent NF-κB pathway
J Yang, Y Su, A Richmond - Free Radical Biology and Medicine, 2007 - Elsevier
… of NF-κB in melanoma and whether ROS scavengers directly or indirectly modify NF-κB activity
of melanoma cells … the apoptosis network in melanoma cell lines via NF-κB, mitochondrial-…
of melanoma cells … the apoptosis network in melanoma cell lines via NF-κB, mitochondrial-…
Ursolic acid induces apoptosis by activating p53 and caspase-3 gene expressions and suppressing NF-κB mediated activation of bcl-2 in B16F-10 melanoma cells
KA Manu, G Kuttan - International immunopharmacology, 2008 - Elsevier
The objective of this study was to assess the effect of ursolic acid, a triterpene on inducing
apoptosis in B16F-10 melanoma cells. Treatment of B16F-10 cells with nontoxic concentration …
apoptosis in B16F-10 melanoma cells. Treatment of B16F-10 cells with nontoxic concentration …
Dimethyl fumarate suppresses metastasis and growth of melanoma cells by inhibiting the nuclear translocation of NF-κB
… the cell viability, migration and invasion in B16BL6 cells [9]. … the cell viability, migration and
invasion in melanoma cell line … cell viability, migration and invasion in mouse melanoma cell …
invasion in melanoma cell line … cell viability, migration and invasion in mouse melanoma cell …
The lymphotoxin-β receptor is an upstream activator of NF-κB-mediated transcription in melanoma cells
P Dhawan, Y Su, YM Thu, Y Yu, P Baugher… - Journal of biological …, 2008 - ASBMB
… of NF-κB in melanoma cells, we examined the effect of activation or inhibition of LTβ-R
signaling pathway on cell proliferation. For these experiments we used Hs294T cells and treated …
signaling pathway on cell proliferation. For these experiments we used Hs294T cells and treated …
Nuclear factor-κB activity correlates with growth, angiogenesis, and metastasis of human melanoma cells in nude mice
S Huang, A DeGuzman, CD Bucana, IJ Fidler - Clinical cancer research, 2000 - AACR
… melanomas is unknown. In this study, we demonstrate that metastatic human melanoma cells
express higher levels of NF-κB … Moreover,IκβαM transfection, which inhibits NF-κB activity (…
express higher levels of NF-κB … Moreover,IκβαM transfection, which inhibits NF-κB activity (…
Melanoma‐derived IL‐1 converts vascular endothelium to a proinflammatory and procoagulatory phenotype via NFκB activation
EA Strozyk, A Desch, B Poeppelmann… - Experimental …, 2014 - Wiley Online Library
… the ability of human melanoma cell lines to activate endothelial cells (ECs) in vitro. Some …
melanoma cells activate ECs either directly and within seconds or by an IL-1-mediated NFκB …
melanoma cells activate ECs either directly and within seconds or by an IL-1-mediated NFκB …
Curcumin‐induced antiproliferative and proapoptotic effects in melanoma cells are associated with suppression of IκB kinase and nuclear factor κB activity and are …
DR Siwak, S Shishodia, BB Aggarwal, R Kurzrock - Cancer, 2005 - Wiley Online Library
… melanoma cell lines to examine its effects on cell viability, apoptosis, and cell signaling
molecules associated with melanoma … critical to the proliferation of melanoma in vitro or in vivo, …
molecules associated with melanoma … critical to the proliferation of melanoma in vitro or in vivo, …
Apoptosis and melanoma: molecular mechanisms
MR Hussein, AK Haemel… - The Journal of Pathology: A …, 2003 - Wiley Online Library
… Melanoma cells can undergo self-destruction via programmed cell death, ie apoptosis. In
these tumours, the molecular components of apoptosis include positive (apoptotic) and …
these tumours, the molecular components of apoptosis include positive (apoptotic) and …