… anticancer effects in SK‑Mel‑28 human malignant melanoma cells via induction of apoptosis, inhibition of cell invasion and modulation of NFκB and MAPK signaling …

P Xiao, B Zheng, J Sun, J Yang - Oncology letters, 2017 - spandidos-publications.com
… studying its effects on NF-κB and MAPK signalling pathway. The results suggest that Biochanin
A inhibits cancer cell growth in SK-Mel-28 melanoma cells in a concentration dependent …

Level of interleukin-8 expression by metastatic human melanoma cells directly correlates with constitutive NF-κB activity

S Huang, A DeGuzman, CD Bucana… - Cytokines, cellular & …, 2000 - Taylor & Francis
… We found that highly metastatic human melanoma cells have a higher level of constitutive
NF-k B activity than low-metastatic counterparts, and that the level of constitutive NF-k B …

MED27 promotes melanoma growth by targeting AKT/MAPK and NF-κB/iNOS signaling pathways

R Tang, X Xu, W Yang, W Yu, S Hou, Y Xuan, Z Tang… - Cancer letters, 2016 - Elsevier
NF-κB. Next, we further analyzed the co-localization of MED27 with NF-κB or p300 in human
melanoma cells (… of MED27 with p300 and NF-κB in melanoma cells, we overexpressed or …

Microcystin-LR promotes melanoma cell invasion and enhances matrix metalloproteinase-2/-9 expression mediated by NF-κB activation

XX Zhang, Z Fu, Z Zhang, C Miao, P Xu… - … science & technology, 2012 - ACS Publications
… the cells lines, MDA-MB-435 melanoma cells showed the highest invasiveness after
microcystin-LR treatment, so we further explored the role of NF-κB … of the melanoma cells exposed …

Andrographolide inhibits melanoma tumor growth by inactivating the TLR4/NF-κB signaling pathway

QQ Zhang, DL Zhou, Y Ding, HY Liu, Y Lei… - Melanoma …, 2014 - journals.lww.com
… In this study, melanoma cells and tumor models were utilized to … NF-κB signaling is the
dominant target of Andro in melanoma, we analyzed the effect of Andro on cell growth in B16 cells

[HTML][HTML] BET inhibitor suppresses melanoma progression via the noncanonical NF-κB/SPP1 pathway

G Deng, F Zeng, J Su, S Zhao, R Hu, W Zhu, S Hu… - Theranostics, 2020 - ncbi.nlm.nih.gov
melanoma cells did not affect the expression of transcriptional factors in the canonical NF-κB
pathway but affected NFKB2 expression in the noncanonical NF-κB pathway. Activation of …

Ginsenoside Rg3 suppresses FUT4 expression through inhibiting NF-κB/p65 signaling pathway to promote melanoma cell death

X Shan, LL Tian, YM Zhang… - International …, 2015 - spandidos-publications.com
… and NF-κB/p65 expression and suppressed melanoma cellcell apoptosis correlated with
its inhibitory effect on NF-κB … Rg3 might be a novel therapy agent for melanoma treatment. …

NF-κB inducing kinase (NIK) modulates melanoma tumorigenesis by regulating expression of pro-survival factors through the β-catenin pathway

YM Thu, Y Su, J Yang, R Splittgerber, S Na, A Boyd… - Oncogene, 2012 - nature.com
… did not significantly diminish the canonical NF-κB activation in WM115 melanoma cells. …
that knocking-down NIK reduced the non-canonical NF-κB activation in melanoma cells. …

Tumor necrosis factor-α blocks apoptosis in melanoma cells when BRAF signaling is inhibited

VC Gray-Schopfer, M Karasarides, R Hayward… - Cancer research, 2007 - AACR
… In melanoma, constitutive NF-κB signaling is associated with … We find that melanoma cells
have elevated basal NF-κB … survival only occurs when NF-κB signaling is further enhanced by …

Nuciferine inhibits skin cutaneous melanoma cell growth by suppressing TLR4/NF-κB signaling

J Xu, A Ying, T Shi - Anti-Cancer Agents in Medicinal Chemistry …, 2020 - ingentaconnect.com
… In this study, we firstly screened the anti-melanoma ability of 2054 compounds from Selleck
melanoma cells, and identified NCFR was the novel candidate against melanoma cell