[HTML][HTML] Amyloid growth and membrane damage: Current themes and emerging perspectives from theory and experiments on Aβ and hIAPP
… between Aβ amyloid growth and membrane damage. In … amyloid peptide are partly associated
membrane composition, peptide sequence, and modes of assembly within the membrane […
membrane composition, peptide sequence, and modes of assembly within the membrane […
Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane
MFM Engel, L Khemtémourian… - Proceedings of the …, 2008 - National Acad Sciences
… results that show fibril growth just before or at the same time as membrane damage, placing
oligomer formation at an even earlier time point than membrane damage. Third, oligomeric …
oligomer formation at an even earlier time point than membrane damage. Third, oligomeric …
Amyloid aggregation: Role of biological membranes and the aggregate–membrane system
M Bucciantini, S Rigacci, M Stefani - The journal of physical …, 2014 - ACS Publications
… the content of membrane cholesterol and … membrane-based mechanisms that could apply
to any amyloidogenic peptide/protein, providing a biochemical background for amyloid growth …
to any amyloidogenic peptide/protein, providing a biochemical background for amyloid growth …
[HTML][HTML] A blend of two resveratrol derivatives abolishes hIAPP amyloid growth and membrane damage
MFM Sciacca, R Chillemi, S Sciuto, V Greco… - … et Biophysica Acta (BBA …, 2018 - Elsevier
… hIAPP's amyloid growth and the related membrane damage as well. Based on this view
and inspired by its known anti-amyloid … both amyloid growth and amyloid mediated POPC/POPS …
and inspired by its known anti-amyloid … both amyloid growth and amyloid mediated POPC/POPS …
[HTML][HTML] A single mutation on the human amyloid polypeptide modulates fibril growth and affects the mechanism of amyloid-induced membrane damage
ARF Hoffmann, MS Saravanan, O Lequin… - … et Biophysica Acta (BBA …, 2018 - Elsevier
… causes considerable damage to the membrane. However, the particular type of damage due
to … of IAPP-induced membrane damage and IAPP fibril growth at the membrane are highly …
to … of IAPP-induced membrane damage and IAPP fibril growth at the membrane are highly …
The role of aromatic side-chains in amyloid growth and membrane interaction of the islet amyloid polypeptide fragment LANFLVH
D Milardi, MFM Sciacca, M Pappalardo… - European Biophysics …, 2011 - Springer
… the membrane-water interface (Wimley and White 1996). Here, we test the importance of
aromatic–aromatic interactions in amyloid formation and peptide-induced membrane damage …
aromatic–aromatic interactions in amyloid formation and peptide-induced membrane damage …
[HTML][HTML] Amyloid-mediated mechanisms of membrane disruption
… interactions are driven by both electrostatic and hydrophobic forces which cooperatively
catalyze amyloid growth on the membrane surface. Zwitterionic 1-palmitoyl-2-oleoyl-sn-glycero-…
catalyze amyloid growth on the membrane surface. Zwitterionic 1-palmitoyl-2-oleoyl-sn-glycero-…
The amyloid-cell membrane system. The interplay between the biophysical features of oligomers/fibrils and cell membrane defines amyloid toxicity
C Cecchi, M Stefani - Biophysical chemistry, 2013 - Elsevier
… It also describes growth and structure of amyloid fibrils and their possible disassembly,
whereas reduced information is available on oligomer structure. Recent research has highlighted …
whereas reduced information is available on oligomer structure. Recent research has highlighted …
[HTML][HTML] Seeding and growth of β-amyloid aggregates upon interaction with neuronal cell membranes
Á Ruiz-Arias, JM Paredes, C Di Biase… - International journal of …, 2020 - mdpi.com
… disease is characterized by the presence of accumulations and deposits of β-amyloid … growth
upon interacting with the cellular membrane, which results in cell permeability and damage …
upon interacting with the cellular membrane, which results in cell permeability and damage …
Amyloid aggregation on lipid bilayers and its impact on membrane permeability
R Friedman, R Pellarin, A Caflisch - Journal of molecular biology, 2009 - Elsevier
… The mechanism of membrane damage due to fibril growth during amyloid aggregation has
been studied here using coarse-grained molecular dynamics simulations. The results shed …
been studied here using coarse-grained molecular dynamics simulations. The results shed …
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