… This paper provides a brief overview of mitochondrial dynamics, mitochondrial dysfunction
in PD, and the Nrf2/ARE system. In addition, recent studies indicating a link between Nrf2 and …

… However, in this study, the knockout (KO) or knockdown (KD) effect of Nrf2/SKN-1 was
not shown and, therefore, other pathways may be involved. This is particularly important to …

… Ferroptosis terminates with mitochondrial dysfunction and toxic lipid peroxidation. Although
conclusive identification of ferroptosis in vivo is challenging, several salient and very well …

… study, the authors demonstrated that NAR could reduce oxidative stress and improve the
mitochondrial dysfunction in vitro via activation of the Nrf2/ARE signaling pathway in neurons. …

… mitochondrial damage and apoptosis. To assess the effects of ATO on … Nrf2 pathway activity,
we analyzed the protein expression levels of Nrf2 and SOD2, a downstream target of Nrf2, …

… the Keap1-Nrf2 pathway in intervertebral disc … mitochondrial dynamics and oxidative
injury in podocytes both in vivo and in vitro and evaluated the role of the Keap1-Nrf2 pathway …

… against oxidative damage and mitochondrial dysfunction associated with Nrf2 activation, we
observed the effect of Daph on the Keap1/Nrf2/ARE antioxidant pathway and the regulation …

… oxidative damage and mitochondrial dysfunction present in PD and AD [3,4]. Oxidative and
… the Nrf2 pathway and mitochondrial function, which we will discuss in the next sections. …

… genes of NRF2, counterbalances the mitochondrial reactive … NRF2 activation and elimination
of mitochondrial dysfunction … of NRF2 pathway in prion diseases to mitigate the disease …

… on mitochondrial function. Inhibition of Pi3K/Akt pathway with LY294002 or silencing of Nrf2
… Therefore, CA activated Nrf2 through modulation of PI3K/Akt pathway resulting in increased …