… increased PI3K/AKT signaling resulted in increased PD-L1 … of the PI3K/AKT pathway and
the expression of PD-L1, the … genes involved in activity of the PI3K/AKT pathway (Table 1). Cell …

… , the PI3K/AKT/mTOR pathway can regulate PD-L1 post-transcription and translation.
Besides, the regulation of the PI3K pathway by the PD-1/PD-L1 … Inhibitors targeting the PD-1/PD-L1 …

… PD-1 blocks activation of PI3K by recruiting SHP-2, but the targeting of PTEN is mediated by
… activation of PI3K and suppresses the signals delivered by the PI3K–Akt pathway. During T …

… -1 and PD-L1 interaction in breast cancer cells. Thus, we hypothesized that the up-… /P-gp
by PD-L1 is mediated by the activation of PI3K/AKT and MAPK/ERK pathways. Indeed, we …

… -1 downstream pathway [53]. First, PD-1 can inhibit the activation of PI3K by recruiting SHP-…
the activation of PI3K and suppresses the PI3K-Akt pathway signal transmission mediated by …

… /STAT signaling pathway [38]. Our research also found that the signaling pathways of
PI3K/AKT and JAK/STAT3 were involved in the expression of PD-L1 induced by IFN-γ. The signal …

… of p-PI3K, p-Akt and p-6s, we confirmed that the PD-1/PD-L1 … PI3K/Akt/mTOR signalling
pathway in GIST cells with high PD… mouse model to explore the PI3K/Akt/mTOR pathway in vivo. …

… Our findings provide evidence for crosstalk between JAK2-STAT1 and PI3K-AKT pathways
in response to IFN-γ in lung adenocarcinoma and have implications for the design of …

… -1/PD-L1 axis, we first detected the protein levels of PI3K/AKT/NF-κB signaling pathway …
activation of PI3K/AKT/NF-κB signaling pathway in MDSC-educated Bregs, we transfected …

… of PD-L1 because treatment with anti-PD-L1 antibody can … that E2 activates PI3K/Akt
pathway to increase PD-L1 protein … through a posttranscriptional mechanism to stabilize PD-L1 …