[HTML][HTML] Placental endoplasmic reticulum stress and oxidative stress in the pathophysiology of unexplained intrauterine growth restriction and early onset …
GJ Burton, HW Yung, T Cindrova-Davies… - Placenta, 2009 - Elsevier
… of greater maternal vascular compromise of the placenta in these cases. We speculate that
… the placental pathology is centred predominantly around endoplasmic reticulum stress, …
… the placental pathology is centred predominantly around endoplasmic reticulum stress, …
Placental endoplasmic reticulum stress negatively regulates transcription of placental growth factor via ATF4 and ATF6β: implications for the pathophysiology of …
M Mizuuchi, T Cindrova‐Davies… - … of pathology, 2016 - Wiley Online Library
… pathophysiology. The early-onset form is commonly associated with growth restriction and
severe placental pathology. A … perfusion and intermittent placental hypoxia. Consequently, the …
severe placental pathology. A … perfusion and intermittent placental hypoxia. Consequently, the …
Endoplasmic reticulum stress and homeostasis in reproductive physiology and pathology
… The resulting placental hypoxia/oxidative stress enhances placental secretion of several
anti angiogenic factor (eg, soluble flt-1 and endoglin), which elicit vascular dysfunction/damage …
anti angiogenic factor (eg, soluble flt-1 and endoglin), which elicit vascular dysfunction/damage …
[HTML][HTML] Endoplasmic reticulum stress is induced in the human placenta during labour
JHW Veerbeek, MCT Van Patot, GJ Burton, HW Yung - Placenta, 2015 - Elsevier
… We recently showed that ER stress might contribute to the pathophysiology of early-onset
PE and IUGR, but not late-onset PE [10]. Our laboratory has previously demonstrated that …
PE and IUGR, but not late-onset PE [10]. Our laboratory has previously demonstrated that …
Endoplasmic reticulum stress responses in placentation-A true balancing act
D Bastida-Ruiz, E Aguilar, A Ditisheim, L Yart, M Cohen - Placenta, 2017 - Elsevier
… in eukaryotes when endoplasmic reticulum stress (ERS) occurs. … placental function. In this
review, we discuss the dual role of UPR activation with respect to its contribution to placental …
review, we discuss the dual role of UPR activation with respect to its contribution to placental …
The endoplasmic reticulum stress of placental impoverishment
CWG Redman - The American Journal of Pathology, 2008 - Elsevier
… This Commentary discusses the key roles of protein synthesis-inhibition and
endoplasmic reticulum (ER) stress in the pathophysiology of intrauterine growth restriction …
endoplasmic reticulum (ER) stress in the pathophysiology of intrauterine growth restriction …
[HTML][HTML] Endoplasmic reticulum stress in the pathogenesis of early-onset pre-eclampsia
GJ Burton, HW Yung - Pregnancy Hypertension: An International Journal of …, 2011 - Elsevier
… reticulum stress in non-laboured placentas from cases of early-onset pre-eclampsia.
Endoplasmic reticulum stress is intricately linked to oxidative stress, … to the placental pathology in …
Endoplasmic reticulum stress is intricately linked to oxidative stress, … to the placental pathology in …
Endoplasmic reticulum stress disrupts placental morphogenesis: implications for human intrauterine growth restriction
HW Yung, M Hemberger, ED Watson… - … of pathology, 2012 - Wiley Online Library
… first evidence of placental endoplasmic reticulum (ER) stress in the pathophysiology of human
intrauterine … In Eif2s1 tm1RjK placentas, we observed increased ER stress and anomalous …
intrauterine … In Eif2s1 tm1RjK placentas, we observed increased ER stress and anomalous …
Mitochondrial–endoplasmic reticulum interactions in the trophoblast: stress and senescence
… Oxidative and endoplasmic reticulum stress signalling … Placental stress has been implicated
in the pathophysiology of … stress, but recently mitochondrial and endoplasmic reticulum …
in the pathophysiology of … stress, but recently mitochondrial and endoplasmic reticulum …
Excessive endoplasmic reticulum stress drives aberrant mouse trophoblast differentiation and placental development leading to pregnancy loss
N Capatina, M Hemberger, GJ Burton… - The Journal of …, 2021 - Wiley Online Library
… homozygous blastocysts and placentas where we observed that chronic ER stress caused
… cell pool, which potentially leads to placental dysmorphogenesis characterised by a small …
… cell pool, which potentially leads to placental dysmorphogenesis characterised by a small …
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