… stress in trophoblast has not been reported in the literature. Hence, we theorized/speculated
that trophoblast cells may undergo ER stress … as representative of placental trophoblast cells …

… Furthermore, we observed premature differentiation of trophoblast progenitors at E9.5 in
mutant placentas, consistent with the in vitro results and with the disproportionate development …

… trophoblast invasion remain unknown. Coincidently, proinflammatory cytokines also induce
ER stress in … the potential role of ER stress in the regulation of trophoblast MMP-2 activity, …

… are a convergence point of various physiological stress stimuli that can be triggered by …
stress on mouse trophoblast differentiation in vitro, mouse blastocyst formation and early placenta …

… endoplasmic reticulum stress, whereas in cases complicated by preeclampsia oxidative stress
… , anti-angiogenic factors and trophoblastic aponecrotic debris into the maternal circulation …

… reticulum stress signalling pathways regulate many aspects of trophoblast behaviour. …
generation of stress within the trophoblast, and consider consequences for obstetric outcome. Mild …

… dysfunction through ER stress in pre-eclamptic placentas. Thus, we demonstrated that
excessive ER stress essentially disrupts homeostasis in trophoblasts in conjunction with …

… , involving functional loss of trophoblast by apoptosis. … villous trophoblast in normally
developing placenta and allows the syncytial fusion. In vitro inactivation of caspase 8 in trophoblast …

… Similarly, sFlt-1 is increased and PlGF decreased in cultured trophoblast cells or placental
villous explants exposed to oxidative stress 21. The pro-angiogenic factors VEGF-A and PlGF …

… in deciduas from FGR and PE+FGR, increased placental levels of pEIF2α have previously
been reported in these cases [15]. In trophoblast-like cell lines, increased levels of pEIF2α …