[HTML][HTML] Phylogenetic study of polyketide synthases and nonribosomal peptide synthetases involved in the biosynthesis of mycotoxins

A Gallo, M Ferrara, G Perrone - Toxins, 2013 - mdpi.com
polyketide and peptide mycotoxins and, for the first time, a phylogenetic analysis of both
PKSs and NRPSs involved in their biosynthesis … involved in mycotoxins biosynthesis grouped …

Recent advancements in the biosynthetic mechanisms for polyketide‐derived mycotoxins

J Huffman, R Gerber, L Du - Biopolymers, 2010 - Wiley Online Library
… enzymes called polyketide synthases (PKSs). This review discusses the biosynthesis of four
toxic … of the molecular mechanisms for the biosynthesis of these mycotoxins. Several of the …

Biosynthesis of sphinganine-analog mycotoxins

L Du, X Zhu, R Gerber, J Huffman, L Lou… - Journal of Industrial …, 2008 - academic.oup.com
polyketide chain releasing found in bacterial and other fungal polyketide biosynthesis
Genetic data suggest that the ketosynthase domain of the polyketide synthase and the chain…

[图书][B] The biosynthesis of mycotoxins: a study in secondary metabolism

P Steyn - 2012 - books.google.com
… microbial metabolites (eg, antibiotics and mycotoxins), which are characteristic of … Mycotoxins
are inherently a heterogeneous group of metabolites that are formed along the polyketide

A PLP-Dependent Polyketide Chain Releasing Mechanism in the Biosynthesis of Mycotoxin Fumonisins in Fusarium verticillioides

R Gerber, L Lou, L Du - Journal of the American Chemical Society, 2009 - ACS Publications
… Fumonisins are polyketide-derived mycotoxins produced by several plant pathogenic fungi.
… chain, which is synthesized by an iterative polyketide synthase (PKS). This PKS does not …

Identification and characterization of the polyketide synthase involved in ochratoxin A biosynthesis in Aspergillus carbonarius

A Gallo, BP Knox, KS Bruno, M Solfrizzo… - International journal of …, 2014 - Elsevier
… a cluster such as most characterized mycotoxins, this PKS was hypothesized … polyketide
synthase AcOTApks allowed us to determine the functional role of this gene in OTA biosynthesis

A polyketide synthase gene required for biosynthesis of fumonisin mycotoxins in Gibberella fujikuroi mating population A

RH Proctor, AE Desjardins, RD Plattner… - Fungal Genetics and …, 1999 - Elsevier
… fumonisins are a product of either polyketide or fatty acid biosynthesis. To isolate a putative
polyketide synthase (PKS) gene involved in fumonisin biosynthesis, we employed PCR with …

Molecular biology of Fusarium mycotoxins

AE Desjardins, RH Proctor - International journal of food microbiology, 2007 - Elsevier
… of mycotoxin biosynthetic genes or gene clusters have been identified in Fusarium to date;
four are polyketide synthase … Other Fusarium mycotoxin biosynthetic genes include a terpene …

A polyketide synthase gene required for ochratoxin A biosynthesis in Aspergillus ochraceus

J O'Callaghan, MX Caddick, ADW Dobson - Microbiology, 2003 - microbiologyresearch.org
… , produced by Aspergillus ochraceus as a polyketide-derived secondary metabolite. A portion
of a putative polyketide synthase gene (pks) involved in the biosynthesis of this mycotoxin

The biosynthesis of polyketide-derived mycotoxins

PS Steyn - Pure and Applied Chemistry Fourth, 1980 - degruyter.com
biosynthesis require further attention, eg the nature of the highly complex polyketide synthetase
secondary metabolites induce the enzymes of aflatoxin biosynthesis; and the loss of the C…