Reveals of new candidate active components in hemerocallis radix and its anti-depression action of mechanism based on network pharmacology approach

HY Lin, JC Tsai, LY Wu, WH Peng - International journal of molecular …, 2020 - mdpi.com
The global depression population is showing a significant increase. Hemerocallis fulva L. is
a common Traditional Chinese Medicine (TCM). Its flower buds are known to have ability to …

Integrating network pharmacology with molecular docking to rationalize the ethnomedicinal use of Alchornea laxiflora (Benth.) Pax & K. Hoffm. for efficient treatment of …

NK Jain, M Tailang, B Chandrasekaran… - Frontiers in …, 2024 - frontiersin.org
Background: Alchornea laxiflora (Benth.) Pax & K. Hoffm.(A. laxiflora) has been indicated in
traditional medicine to treat depression. However, scientific rationalization is still lacking …

[HTML][HTML] Exploring the mechanisms of action of Cordyceps sinensis for the treatment of depression using network pharmacology and molecular docking

X Zhang, M Wang, Y Qiao, Z Shan, M Yang… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background Depression is the most common type of psychological disorder, with
continuous, prolonged, and persistent bad moods as the main clinical feature. Cordyceps …

Integrating Network Pharmacology, Molecular Docking and Pharmacological Evaluation for Exploring the Polyrhachis vicina Rogers in Ameliorating Depression

J He, D Han, C Jia, J Xie, F Zhu, J Wei, D Li… - Drug Design …, 2023 - Taylor & Francis
Purpose To investigate the mechanisms of antidepressant action of active fraction of
Polyrhachis vicina Rogers (AFPR) through network pharmacology, molecular docking and …

A network pharmacology and molecular docking approach to reveal the mechanism of Chaihu Anxin Capsule in depression

L Yang, Y Zhao, R Qu, Y Fu, C Zhou… - Frontiers in Endocrinology, 2023 - frontiersin.org
Introduction As one of the most frequently diagnosed mental disorders, depression is
expected to become the most common disease worldwide by 2030. Previous studies have …

Anti-depressant components and mechanism of Rehmanniae Radix based on UPLC-Q-Orbitrap HRMS and network pharmacology

DE Han, ZS Yue, HW Li, GZ Liu, BR Cai… - Zhongguo Zhong yao za …, 2022 - europepmc.org
This study aimed to explore the anti-depressant components of Rehmanniae Radix and its
action mechanism based on network pharmacology combined with molecular docking. The …

Rapid action of mechanism investigation of Yixin Ningshen tablet in treating depression by combinatorial use of systems biology and bioinformatics tools

R Wu, H Wang, X Lv, X Shen, G Ye - Journal of ethnopharmacology, 2020 - Elsevier
Abstract Ethnopharmacological relevance Yixin Ningshen tablet is a CFDA-approved TCM
formula for treating depression clinically. However, little is known about its active …

An integrative metabolomics and network pharmacology method for exploring the effect and mechanism of Radix Bupleuri and Radix Paeoniae Alba on anti …

H Zhang, S Zhang, M Hu, Y Chen, W Wang… - … of pharmaceutical and …, 2020 - Elsevier
Depression is a common mental illness, which is caused by 'liver qi stagnationin in
traditional Chinese medicine (TCM) theory. Thus, relieving “liver qi stagnation” is considered …

[HTML][HTML] Integrated network pharmacology and hepatic metabolomics to reveal the mechanism of Acanthopanax senticosus against major depressive disorder

X Gu, G Zhang, Q Wang, J Song, Y Li, C Xia… - Frontiers in Cell and …, 2022 - frontiersin.org
Objective: Acanthopanax senticosus (Rupr. et Maxim.) Harms (ASH) is a traditional herbal
medicine widely known for its antifatigue and antistress effects, as well as tonifying qi …

Molecular mechanism of Epicedium treatment for depression based on network pharmacology and molecular docking technology

Y Dong, B Tao, X Xue, C Feng, Y Ren, H Ma… - … medicine and therapies, 2021 - Springer
Background Increasing attention has been paid to the effect of Epimedium on the nervous
system, particularly anti-depression function. In the present study, we applied network …