Metabolism of phosphatidylcholine and its implications for lipid acyl chain composition in Saccharomyces cerevisiae

AIPM de Kroon - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2007 - Elsevier
Phosphatidylcholine (PC) is a very abundant membrane lipid in most eukaryotes including
the model organism Saccharomyces cerevisiae. Consequently, the molecular species …

[HTML][HTML] The Saccharomyces cerevisiae INO4 gene encodes a small, highly basic protein required for derepression of phospholipid biosynthetic enzymes.

DK Hoshizaki, JE Hill, SA Henry - Journal of Biological Chemistry, 1990 - Elsevier
The INO4 gene product is believed to be a positive regulatory factor in a complex cascade of
positive and negative factors that coordinates the synthesis of phospholipids in the yeast …

Isolation and characterization of a mutant of Saccharomyces cerevisiae with pleiotropic deficiencies in transcriptional activation and repression.

E Lamping, J Lückl, F Paltauf, SA Henry… - Genetics, 1994 - academic.oup.com
The isolation of the dep1 mutant of Saccharomyces cerevisiae is reported. The mutant was
identified by its disability to regulate expression of structural genes involved in phospholipid …

Redirection of lipid flux toward phospholipids in yeast increases fatty acid turnover and secretion

R Ferreira, PG Teixeira, V Siewers… - Proceedings of the …, 2018 - National Acad Sciences
Bio-based production of fatty acids and fatty acid-derived products can enable sustainable
substitution of petroleum-derived fuels and chemicals. However, developing new microbial …

Metabolism and functions of phosphatidylserine

JE Vance, R Steenbergen - Progress in lipid research, 2005 - Elsevier
Phosphatidylserine (PS) is a quantitatively minor membrane phospholipid that is
synthesized by prokaryotic and eukaryotic cells. In this review we focus on genes and …

Regulation of phosphatase synthesis in Saccharomyces cerevisiae—a review

Y Oshima, N Ogawa, S Harashima - Gene, 1996 - Elsevier
Transcription of the genes encoding acid and alkaline phosphatases and the inorganic
phosphate (Pi) transporter of Saccharomyces cerevisiae are coordinately repressed and …

Cell cycle regulation of membrane phospholipid metabolism

S Jackowski - Journal of Biological Chemistry, 1996 - ASBMB
This review focuses on the phospholipid metabolism regulated by the cell cycle.
Phospholipids are the major cellular constituents required for the assembly of biological …

Phosphoinositide signaling and the regulation of membrane trafficking in yeast

G Odorizzi, M Babst, SD Emr - Trends in biochemical sciences, 2000 - cell.com
Phosphoinositides are key regulators of diverse cellular processes in eukaryotic cells.
Genetic studies in yeast have advanced our understanding of how phosphoinositide …

Yeast mutant defective in phosphatidylserine synthesis.

K Atkinson, S Fogel, SA Henry - Journal of Biological Chemistry, 1980 - ASBMB
Phospholipid biosynthesis in a mutant of Saccharomyces cerevisiae (cho1) which lacks
phosphatidylserine (Atkinson, KD, Jensen, B., Storm, E., Kolat, AI, Henry, SA & Fogel …

Phosphatidylcholine biosynthesis via the CDP-choline pathway in Saccharomyces cerevisiae. Multiple mechanisms of regulation.

CR McMaster, RM Bell - Journal of Biological Chemistry, 1994 - Elsevier
Multiple mechanisms of regulation in the CDP-choline pathway for phosphatidylcholine (PC)
synthesis were revealed by exploring the effects of choline and inositol on this pathway in …