Catalytic nanozymes for central nervous system disease

K Chen, S Sun, J Wang, XD Zhang - Coordination Chemistry Reviews, 2021 - Elsevier
The central nervous system (CNS) is a centralized control system for the human body, and
minor lesions or injuries will cause inestimable consequences. Due to high oxygen …

Nanozyme-based strategies for efficient theranostics of brain diseases

R Xu, S Zhang, P Wang, R Zhang, P Lin, Y Wang… - Coordination Chemistry …, 2024 - Elsevier
Oxidative stress emerges as a critical mechanism underlying the development and
progression of various brain diseases, arising from either increased generation of reactive …

Bioactive material-based nanozymes with multifunctional attributes for biomedicine: expanding antioxidant therapeutics for neuroprotection, cancer, and anti …

DO Lopez-Cantu, RB González-González… - Coordination Chemistry …, 2022 - Elsevier
Considering the biochemical rationale, the deployments of enzymes as therapeutic targets
against several oxidative stress-related diseases have been hindered by the limitations of …

Nanozyme enabled protective therapy for neurological diseases

F Cheng, S Kotha, M Fu, Q Yang, H Wang, W He… - Nano Today, 2024 - Elsevier
Nanozymes are nanomaterials that mimic enzymatic activities found in natural human
biological processes. Nanozymes can perform reactive oxidative species (ROS) scavenging …

Multi-enzyme activity nanozymes for biosensing and disease treatment

L Su, S Qin, Z Xie, L Wang, K Khan, AK Tareen… - Coordination Chemistry …, 2022 - Elsevier
In cells, multi-step biochemical reactions catalyzed by multi-enzyme biocatalysts are critical.
While, multi-enzyme biocatalysts have evolved to catalyze these diverse reactions in …

[HTML][HTML] The applications of nanozymes in neurological diseases: from mechanism to design

Y Zhang, L Zhang, M Wang, P Li - Theranostics, 2023 - ncbi.nlm.nih.gov
Nanozymes are a class of nanomaterials with enzyme-like catalytic activities. Due to their
multiple catalytic activities, as well as their good stability, modifiable activity and other …

Structure design mechanisms and inflammatory disease applications of nanozymes

Y Lu, C Cao, X Pan, Y Liu, D Cui - Nanoscale, 2023 - pubs.rsc.org
Nanozymes are artificial enzymes with high catalytic activity, low cost, and good
biocompatibility, and have received ever-increasing attention in recent years. Various …

Breakthroughs in nanozyme-inspired application diversity

Q Zhang, L Song, K Zhang - Materials Chemistry Frontiers, 2023 - pubs.rsc.org
The rapid advancement of nanomaterials has promoted the booming of nanozymes capable
of mimicking natural enzymes. As ideal alternatives to natural enzymes, nanozymes are …

Nanozymes regulate redox homeostasis in ROS-related inflammation

Q Li, Y Liu, X Dai, W Jiang, H Zhao - Frontiers in Chemistry, 2021 - frontiersin.org
Reactive oxygen species (ROS), in moderate amounts, play an essential role in regulating
different physiological functions in organisms. However, increased amounts of ROS may …

Inorganic nanozymes: prospects for disease treatments and detection applications

P Wang, D Min, G Chen, M Li, L Tong, Y Cao - Frontiers in Chemistry, 2021 - frontiersin.org
In recent years, with the development of nanomaterials, a slice of nanomaterials has been
demonstrated to possess high catalytic activity similar to natural enzymes and counter the …