Riboflavin transporter is finally identified

Y Moriyama - The journal of biochemistry, 2011 - academic.oup.com
Riboflavin or vitamin B2 is one of the constituents of energy drinks. Although this compound
is known to be absorbed in the intestine and that it circulates throughout the body and is …

Identification and functional characterization of a novel human and rat riboflavin transporter, RFT1

A Yonezawa, S Masuda… - American Journal of …, 2008 - journals.physiology.org
Absorption of riboflavin is mediated by transporter (s). However, a mammalian riboflavin
transporter has yet to be identified. In the present study, the novel human and rat riboflavin …

Flavin binding to the high affinity riboflavin transporter RibU

RH Duurkens, MB Tol, ER Geertsma… - Journal of Biological …, 2007 - ASBMB
The first biochemical and spectroscopic characterization of a purified membrane transporter
for riboflavin (vitamin B 2) is presented. The riboflavin transporter RibU from the bacterium …

[HTML][HTML] Functional characteristics of the human ortholog of riboflavin transporter 2 and riboflavin-responsive expression of its rat ortholog in the small intestine indicate …

M Fujimura, S Yamamoto, T Murata, T Yasujima… - The Journal of …, 2010 - Elsevier
Riboflavin transporter (RFT) 2 has recently been identified as a transporter that may be,
mainly based on the functional characteristics of its rat ortholog (rRFT2), involved in the …

Functional involvement of RFVT3/SLC52A3 in intestinal riboflavin absorption

H Yoshimatsu, A Yonezawa, Y Yao… - American Journal …, 2014 - journals.physiology.org
Riboflavin, also known as vitamin B2, is transported across the biological membrane into
various organs by transport systems. Riboflavin transporter RFVT3 is expressed in the small …

Identification and functional characterization of rat riboflavin transporter 2

S Yamamoto, K Inoue, K Ohta, R Fukatsu… - Journal of …, 2009 - academic.oup.com
We have newly identified rat riboflavin transporter 2 (rRFT2) and its human orthologue
(hRFT2), and carried out detailed functional characterization of rRFT2. The mRNA of rRFT2 …

Carrier‐mediated transport of riboflavin in the rat colon

H Yuasa, M Hirobe, S Tomei… - … & drug disposition, 2000 - Wiley Online Library
Carriers involved in riboflavin transport have generally been presumed to be localized in the
upper small intestine. However, using a closed loop technique, we found that in the rat colon …

[HTML][HTML] Identification and comparative functional characterization of a new human riboflavin transporter hRFT3 expressed in the brain

Y Yao, A Yonezawa, H Yoshimatsu, S Masuda… - The Journal of …, 2010 - Elsevier
We isolated cDNA coding a new human riboflavin transporter (hRFT) 3, which exhibits 86.7
and 44.1% amino acid identity with hRFT1 and hRFT2, respectively. It was predicted to have …

Structure/functional aspects of the human riboflavin transporter-3 (SLC52A3): role of the predicted glycosylation and substrate-interacting sites

VS Subramanian, S Sabui… - … of Physiology-Cell …, 2017 - journals.physiology.org
The human riboflavin (RF) transporter-3 (hRFVT-3; product of the SLC52A3 gene) plays an
essential role in the intestinal RF absorption process and is expressed exclusively at the …

Identification of residues/sequences in the human riboflavin transporter-2 that is important for function and cell biology

VS Subramanian, R Kapadia, A Ghosal, HM Said - Nutrition & metabolism, 2015 - Springer
Background Riboflavin (RF) is essential for normal cellular metabolic activities. Human cells
obtain RF from their surroundings via a carrier-mediated process that involves RF …