Epidemiologic studies have identified cocaine as a cofactor for development of acquired
immunodeficiency syndrome (AIDS). To evaluate this interaction, human peripheral blood …

Previous studies haveshown that cocaineconsumption alters the normal immune functions
of animals. Several epidemiologicstudies have indicated an association between cocaine …

The pathogenesis of AIDS is a complex and prolonged process that is affected by a variety
of cofactors, including the abuse of both intravenous and smoked (crack) cocaine. The exact …

Cocaine and CMV each have been suggested to promote the progression of HIV-1 infection.
In the present study, the interaction of cocaine and CMV was investigated in a PBMC …

To examine whether recent intravenous use of cocaine might be associated with increased
risk of human immunodeficiency virus type 1 (HIV) infection, the authors studied 2,597 active …

Cocaine use is an important high risk behavior in the AIDS epidemic. In this study, we tested
the hypothesis that cocaine potentiates the replication of HIV-1 in human PBMC. A coculture …

In recent years, drug abuse has been identified as the most important factor in the spread of
the AIDS epidemic (1). In the injection drug use (IDU) population, the sharing of …

Over 1.2 million people in the United States are infected with the human immunodeficiency
virus type 1 (HIV-1). Tremendous progress has been made over the past three decades on …

Recent in vitro and in vivo research has suggested that cocaine has a direct effect on the
pathogenesis of AIDS. These findings are confirmed by epidemiological studies linking the …

Cocaine-related immunosuppression is asumed to have serious consequences, but its
evaluation in drug-addicted subjects is lacking. In this study performed with materials from …