Self-polymerized polydopamine-based nanoparticles for acute kidney injury treatment through inhibiting oxidative damages and inflammatory

B Zheng, G Deng, J Zheng, Y Li, B Wang, X Ding… - … International Journal of …, 2022 - Elsevier
The polydopamine nanoparticles (PDA NPs) as a self-polymerized form of dopamine have
occurred with growing interest in biomedical applications in late years. Its natural-inspired …

ROS responsive polydopamine nanoparticles to relieve oxidative stress and inflammation for ameliorating acute inflammatory bowel

M Yan, L Zhu, S Wu, Y Cao, N Mou, Q Chi, G Wang… - Biomaterials …, 2022 - Elsevier
Oxidative stress is a key factor in the development of inflammatory diseases. Elimination of
reactive oxygen species (ROS) in the inflamed colon has been confirmed as an effective …

Engineered biomimetic nanoplatform protects the myocardium against ischemia/reperfusion injury by inhibiting pyroptosis

Y Wei, M Zhu, S Li, T Hong, X Guo, Y Li… - … Applied Materials & …, 2021 - ACS Publications
Protection of cardiomyocytes against oxidative stress is vital to alleviate myocardial
ischemia/reperfusion injury (MI/RI). However, antioxidative treatment is hampered by the …

Melanin-like polydopamine nanoparticles mediating anti-inflammatory and rescuing synaptic loss for inflammatory depression therapy

T Zhu, H Wang, H Gu, L Ju, X Wu, W Pan… - Journal of …, 2023 - Springer
Inflammatory depression is closely related to neuroinflammation. However, current anti-
inflammatory drugs have low permeability to cross blood–brain barrier with difficulties …

[HTML][HTML] Polydopamine nanoparticles for the treatment of acute inflammation-induced injury

H Zhao, Z Zeng, L Liu, J Chen, H Zhou, L Huang… - Nanoscale, 2018 - pubs.rsc.org
Nanotechnology-mediated anti-inflammatory therapy is emerging as a novel strategy for the
treatment of inflammation-induced injury. However, one of the main hurdles for these anti …

Restoring cellular calcium homeostasis to rescue ER stress by 1, 2-bis (2-aminophenoxy) ethane-N, N, N′, N′-tetraacetic acid acetoxymethyl ester-loaded lipid …

J Zhang, J Yan, Y Wang, H Liu, X Sun, Y Gu, L Yu… - Chinese Chemical …, 2024 - Elsevier
Early pathogenesis of ischemia-reperfusion (I/R)-induced acute kidney injury (AKI) is
dominated by intracellular calcium overload, which induces oxidative stress, intracellular …

A polymeric nanosponge as a broad-spectrum reactive oxygen species scavenger for acute kidney injury treatment

S He, C Chen, F Li, W Xu, D Li, M Liang, X Yang - Nano Letters, 2023 - ACS Publications
Acute kidney injury (AKI) is closely associated with the overproduction of reactive oxygen
species (ROS), which can cause multiple organ dysfunctions without timely treatment …

Drug-Loaded Mesoporous Polydopamine Nanoparticles in Chitosan Hydrogels Enable Myocardial Infarction Repair through ROS Scavenging and Inhibition of …

T Wang, Y Wang, Y Zhang, Z Fang, S Li… - … Applied Materials & …, 2024 - ACS Publications
In this study, we synthesized mesoporous polydopamine nanoparticles (MPDA NPs) using
an emulsion-induced interface assembly strategy and loaded epigallocatechin gallate …

Polydopamine nanoparticles as dual-task platform for osteoarthritis therapy: A scavenger for reactive oxygen species and regulator for cellular powerhouses

X Wang, H Zhao, Z Liu, Y Wang, D Lin, L Chen… - Chemical Engineering …, 2021 - Elsevier
Because of the obscure etiology of osteoarthritis (OA) and unsatisfactory treatment
outcomes, new effective and minimally invasive therapies are urgently needed. Oxidative …

Evaluation of reactive oxygen species scavenging of polydopamine with different nanostructures

Y Zheng, X Chen, Q Zhang, L Yang… - Advanced …, 2024 - Wiley Online Library
Reactive oxygen species (ROS) play an important role in cellular metabolism and many
oxidative stress‐related diseases, while excessive accumulation of ROS will lead to genetic …