Alpha 1 Antitrypsin deficiency (AATD) is a hereditary condition characterized by low serum
Alpha 1 Antitrypsin (AAT) levels and a predisposition towards early-onset emphysema …

Abstract Introduction Alpha-1 antitrypsin (AAT) deficiency is an autosomal co-dominant
genetic condition that predisposes individuals to pulmonary and hepatic disease, and in …

Abstract Alpha-1 antitrypsin deficiency (AATD) is a largely monogenetic disorder associated
with a high risk for the development of chronic obstructive pulmonary disease (COPD) and …

Augmentation therapy with intravenous alpha-1 antitrypsin is the only specific treatment for
alpha-1 antitrypsin deficiency (AATD)-associated emphysema. This treatment has been …

Patients with severe alpha-1 antitrypsin deficiency (AATD) have increased risk of developing
chronic, progressive lung disease, particularly pan-lobular emphysema. 1 P athogenesis is …

α-1 antitrypsin deficiency (AATD) is an autosomal co-dominant condition characterized by
low circulating levels of α-1 antitrypsin (AAT), a serine protease inhibitor. Significant work …

The underdiagnosis of alpha-1 antitrypsin (AAT) deficiency (AATD) has been recognized for
many years, yet little progress has been made in treatment of the disease. In this review, we …

Management of lung disease in patients with alpha-1 antitrypsin deficiency (AATD) includes
both non-pharmacological and pharmacological approaches. Lifestyle changes with …

Background Alpha‐1 antitrypsin deficiency is an inherited disorder that can cause chronic
obstructive pulmonary disease (COPD). People who smoke are more seriously affected and …

Abstract Alpha-1 antitrypsin deficiency (AATD) is a rare and underdiagnosed genetic
predisposition for COPD and emphysema and other conditions, including liver disease …