The investigation of MCM-48-type and MCM-41-type mesoporous silica as oral solid dispersion carriers for water insoluble cilostazol

Y Wang, L Sun, T Jiang, J Zhang, C Zhang… - Drug development …, 2014 - Taylor & Francis
Objective: To explore the suitable application of MCM-41 (Mobil Composition of Matter
number forty-one)-type and MCM-48-type mesoporous silica in the oral water insoluble drug …

Effect of amine functionalization of spherical MCM-41 and SBA-15 on controlled drug release

A Szegedi, M Popova, I Goshev, J Mihály - Journal of solid state chemistry, 2011 - Elsevier
Abstract MCM-41 and SBA-15 silica materials with spherical morphology and different
particle sizes were synthesized and modified by post-synthesis method with 3 …

New method for preparation of delivery systems of poorly soluble drugs on the basis of functionalized mesoporous MCM-41 nanoparticles

M Popova, A Szegedi, K Yoncheva… - Microporous and …, 2014 - Elsevier
MCM-41 silica with spherical morphology and small particle sizes (100 nm) was synthesized
and modified by post-synthesis method with amino and/or carboxylic groups. Solid state …

Study on formulation variables of methotrexate loaded mesoporous MCM-41 nanoparticles for dissolution enhancement

N Vadia, S Rajput - European journal of pharmaceutical sciences, 2012 - Elsevier
The aim of this study was to develop methotrexate loaded mesoporous MCM-41
nanoparticles for improved dissolution of methotrexate. The mesoporous MCM-41 …

3D cubic mesoporous silica microsphere as a carrier for poorly soluble drug carvedilol

Y Hu, Z Zhi, Q Zhao, C Wu, P Zhao, H Jiang… - Microporous and …, 2012 - Elsevier
The present work was proposed not only to exploit the potential of 3D cage-like mesoporous
silica SBA-16 with a well-defined spherical morphology as a carrier for poorly soluble drugs …

[HTML][HTML] Mesoporous drug carrier systems for enhanced delivery rate of poorly water-soluble drug: nimodipine

A Kiwilsza, B Milanowski, K Drużbicki, LE Coy… - Journal of Porous …, 2015 - Springer
Two mesoporous silica materials: MCM-41 and SBA-15 were applied as potential
nanocarriers for poorly soluble drug—nimodipine. Drug incorporation was performed using …

Exploitation of 3D face-centered cubic mesoporous silica as a carrier for a poorly water soluble drug: Influence of pore size on release rate

W Zhu, L Wan, C Zhang, Y Gao, X Zheng… - Materials Science and …, 2014 - Elsevier
The purposes of the present work were to explore the potential application of 3D face-
centered cubic mesoporous silica (FMS) with pore size of 16.0 nm as a delivery system for …

Mesoporous silica as a support for poorly soluble drug: Influence of pH and amino group on the drug release

L Latifi, S Sohrabnezhad, M Hadavi - Microporous and Mesoporous …, 2017 - Elsevier
Two different structures of mesoporous silica materials (MSMs), MCM-41 and MCM-41-NH
2, were studied to investigate their suitability for drug delivery systems (DDS). The …

In vitro and in vivo evaluation of ordered mesoporous silica as a novel adsorbent in liquisolid formulation

B Chen, Z Wang, G Quan, X Peng, X Pan… - International journal …, 2012 - Taylor & Francis
Background A liquisolid technique has been reported to be a new approach to improve the
release of poorly water-soluble drugs for oral administration. However, an apparent …

Improvement of solubility of celecoxib by inclusion in MCM-41 mesoporous silica: drug loading and release

Ş GÜNAYDIN, A YILMAZ - Turkish Journal of Chemistry, 2015 - journals.tubitak.gov.tr
Celecoxib is a poorly water-soluble nonsteroidal anti-inflammatory drug. Here we report four
ordered mesoporous silica MCM-41 supports with different particle size, pore volume, and …