The role of inflammation in mouse pulmonary neoplasia
AK Bauer, EA Rondini - Veterinary pathology, 2009 - journals.sagepub.com
Inflammation is a risk factor for the development of many types of neoplasia, including skin,
colon, gastric, and mammary cancers, among others. Chronic pulmonary diseases, such as …
colon, gastric, and mammary cancers, among others. Chronic pulmonary diseases, such as …
Relationship between lung carcinogenesis and chronic inflammation in rodents
Y Nakano-Narusawa, M Yokohira, K Yamakawa, J Ye… - Cancers, 2021 - mdpi.com
Simple Summary Lung cancer is the most common cause of cancer-related deaths
worldwide. There are various risk factors for lung cancer, including tobacco smoking …
worldwide. There are various risk factors for lung cancer, including tobacco smoking …
Inflammation-related carcinogenesis: Lessons from animal models to clinical aspects
F Okada, R Izutsu, K Goto, M Osaki - Cancers, 2021 - mdpi.com
Simple Summary In multicellular organisms, inflammation is the body's most primitive and
essential protective response against any external agent. Inflammation, however, not only …
essential protective response against any external agent. Inflammation, however, not only …
Lipopolysaccharide enhances mouse lung tumorigenesis: a model for inflammation-driven lung cancer
T Melkamu, X Qian, P Upadhyaya… - Veterinary …, 2013 - journals.sagepub.com
The association between pulmonary inflammation and lung cancer is well established.
However, currently there are no appropriate models that recapitulate inflammation-related …
However, currently there are no appropriate models that recapitulate inflammation-related …
Inflammation and lung carcinogenesis: applying findings in prevention and treatment
KA Peebles, JM Lee, JT Mao, S Hazra… - Expert review of …, 2007 - Taylor & Francis
Lung carcinogenesis is a complex process requiring the acquisition of genetic mutations that
confer the malignant phenotype as well as epigenetic alterations that may be manipulated in …
confer the malignant phenotype as well as epigenetic alterations that may be manipulated in …
RNA-sequencing studies identify genes differentially regulated during inflammation-driven lung tumorigenesis and targeted by chemopreventive agents
X Qian, A Khammanivong, JM Song, F Teferi… - Inflammation …, 2015 - Springer
Introduction Chronic pulmonary inflammation has been consistently shown to increase the
risk of lung cancer. Therefore, assessing the molecular links between the two diseases and …
risk of lung cancer. Therefore, assessing the molecular links between the two diseases and …
Susceptibility to neoplastic and non-neoplastic pulmonary diseases in mice: genetic similarities
AK Bauer, AM Malkinson… - American Journal of …, 2004 - journals.physiology.org
Chronic inflammation predisposes toward many types of cancer. Chronic bronchitis and
asthma, for example, heighten the risk of lung cancer. Exactly which inflammatory mediators …
asthma, for example, heighten the risk of lung cancer. Exactly which inflammatory mediators …
The potential contributions of chronic inflammation to lung carcinogenesis
S Ballaz, JL Mulshine - Clinical lung cancer, 2003 - Elsevier
A number of lines of evidence suggests that chronic inflammation contributes to the process
of carcinogenesis. In this article, this theme is explored with particular emphasis on the …
of carcinogenesis. In this article, this theme is explored with particular emphasis on the …
Early gene expression differences in inbred mouse strains with susceptibility to pulmonary adenomas
TM Stearns, CL Cario, HS Savage, JP Sundberg… - … and molecular pathology, 2012 - Elsevier
Lung cancer is the most common cause of cancer-related deaths in both men and women,
and effective preventatives are rare due to the difficulty of early detection. Specific gene …
and effective preventatives are rare due to the difficulty of early detection. Specific gene …
Transcriptome of normal lung distinguishes mouse lines with different susceptibility to inflammation and to lung tumorigenesis
AIRmax and AIRmin mouse lines show a differential lung inflammatory response and
differential lung tumor susceptibility after urethane treatment. The transcript profile of∼ …
differential lung tumor susceptibility after urethane treatment. The transcript profile of∼ …