HTLV-III/LAV-Neutralizing Antibodies to an E. coli-Produced Fragment of the Virus Envelope

SD Putney, TJ Matthews, WG Robey, DL Lynn… - Science, 1986 - science.org
Immunization with either an Escherichia coli recombinant segment of the human T-cell
lymphotropic virus (HTLV-III/LAV) envelope protein (gp120) or with deglycosylated gp120 …

Antiserum to a synthetic peptide recognizes the HTLV-III envelope glycoprotein

RC Kennedy, RD Henkel, D Pauletti, JS Allan, TH Lee… - Science, 1986 - science.org
In a study performed to determine which regions of the human T-cell lymphotrophic virus
type III (HTLV-III) may represent vaccine candidates to prevent the acquired immune …

Major glycoprotein antigens that induce antibodies in AIDS patients are encoded by HTLV-III

JS Allan, JE Coligan, F Barin, MF McLane, JG Sodroski… - Science, 1985 - science.org
Antibodies from the serum of patients with the acquired immune deficiency syndrome (AIDS)
or with the AIDS-related complex and from the serum of seropositive healthy homosexuals …

Binding of HTLV-III/LAV to T4+ T Cells by a Complex of the 110K Viral Protein and the T4 Molecule

JS McDougal, MS Kennedy, JM Sligh, SP Cort… - Science, 1986 - science.org
Human T-lymphotropic virus type III (HTLV-III) or lymphadenopathy-associated virus (LAV) is
tropic for human T cells with the helper-inducer phenotype, as defined by reactivity with …

Characterization of gp41 as the transmembrane protein coded by the HTLV-III/LAV envelope gene

FDM Veronese, AL DeVico, TD Copeland, S Oroszlan… - Science, 1985 - science.org
Radiolabeled amino acid sequencing was used to characterize gp41, an antigen of HTLV-
III/LAV, the virus believed to be the etiological agent of the acquired immune deficiency …

Virus envelope protein of HTLV-III represents major target antigen for antibodies in AIDS patients

F Barin, MF McLane, JS Allan, TH Lee, JE Groopman… - Science, 1985 - science.org
In this study, two glycoproteins (gp160 and gp120) that are encoded by human T-cell
lymphoma virus type III (HTLV-III) were the antigens most consistently recognized by …

Expression of the HTLV-III envelope gene by a recombinant vaccinia virus

S Chakrabarti, M Robert-Guroff, F Wong-Staal… - Nature, 1986 - nature.com
The discovery that the aetiological agent of acquired immune deficiency syndrome (AIDS) is
a retro virus, referred to as human T-lymphotropic virus type III (HTLV-III) or …

Induction of anti‐HIV neutralizing antibodies by synthetic peptides.

TC Chanh, GR Dreesman, P Kanda, GP Linette… - The EMBO …, 1986 - embopress.org
Two synthetic peptides containing amino acid sequences analogous to the envelope
glycoprotein of human T‐lymphotropic virus (HTLV) type III (HTLV‐III) and lymphadenopathy …

A new HTLV-III/LAV encoded antigen detected by antibodies from AIDS patients

JS Allan, JE Coligan, TH Lee, MF McLane, PJ Kanki… - Science, 1985 - science.org
A newly identified protein from HTLV-III/LAV, the virus implicated as the etiologic agent of the
acquired immune deficiency syndrome, was studied. This protein, which has a molecular …

Characterization of a human immunodeficiency virus neutralizing monoclonal antibody and mapping of the neutralizing epitope

S Matsushita, M Robert-Guroff, J Rusche… - Journal of …, 1988 - Am Soc Microbiol
A monoclonal antibody was produced to the exterior envelope glycoprotein (gp120) of the
human T-cell lymphotropic virus (HTLV)-IIIB isolate of the human immunodeficiency virus …