Effect of theophylline on the intestinal clearance of drugs in rats

CH Bair, JD Huang - Journal of pharmacy and pharmacology, 1992 - academic.oup.com
Intestinal eχsorption of salicylic acid, urea and quinidine was measured during the perfusion
of the rat intestinal lumen with Tyrode solution. The intestinal clearance (CLi) of the three …

Concentration-dependent exsorption of quinidine in the rat intestine

CH Bair, MJ Tang, JD Huang - Journal of pharmacy and …, 1992 - academic.oup.com
During intravenous infusion, the luminal concentration of quinidine was higher than the
plasma concentration. The intestinal clearance (CLi) of the drug was measured by dividing …

In Vivo Absorption of Theophylline and Salicylic Acid from Rat Small Intestine

Ö Johansson, T Lindberg… - Acta pharmacologica et …, 1984 - Wiley Online Library
In vivo absorption of theophylline and salicylic acid from the rat small intestine was studied
by a closed segment technique. The drugs were administered at 1 and 4 mM in dissolved …

Role of unstirred water layer in the exsorption of quinidine

JD Huang - Journal of pharmacy and pharmacology, 1990 - academic.oup.com
Intestinal exsorption of salicylic acid, thiopentone, theophylline, and quinidine was
measured during perfusion of the intestinal lumen with Tyrode solution. The effect of pectin …

Factors influencing absorption and excretion of drugs. IV. Effect of hypertonic and hypotonic solutions on in situ rat intestinal absorption of several drugs

S KOJIMA, J MIYAKE - Chemical and Pharmaceutical Bulletin, 1975 - jstage.jst.go.jp
抄録 The effect of the hypertonic and hypotonic solutions on the absorption of acetanilide,
salicylamide, sulfisoxazole, and quinine from rat small intestine was studied using the in situ …

Effect of cigarette smoking on theophylline pharmacokinetics in rats

Y Gomita, K Furuno, K Eto, M Okazaki… - Journal of pharmacy …, 1991 - Wiley Online Library
The effect of acute cigarette smoke inhalation on the plasma levels of theophylline
administered orally and parenterally to rats has been studied. The animals were exposed to …

Dose-dependency in the exsorption of theophylline and the intestinal dialysis of theophylline by oral activated charcoal in rats

K Arimori, M Nakano - Journal of pharmacy and pharmacology, 1988 - academic.oup.com
The elimination half-life of theophylline in serum after intravenous (iv) administration of
aminophylline increased with increase in dose. Exsorption of theophylline from blood to the …

Transport of theophylline from blood to the intestinal lumen following iv administration to rats

K ARIMORI, M NAKANO - Journal of pharmacobio-dynamics, 1985 - jstage.jst.go.jp
EH 6.0 isotonic phosphate buffer, and were 2.71 and 2.32 h or pH 8.0 isotonic phosphate
uffer, respectively. The amounts of theophylline excreted in the perfusate and the bile juice …

Effects of salicylate on rectal absorption of theophylline

T Nishihata, JH Rytting, T Higuchi - Journal of Pharmaceutical …, 1981 - Wiley Online Library
The rectal absorption of theophylline in rats was facilitated by concurrent administration of
salicylic acid or sodium salicylate. The absorption of theophylline depended on the …

Influence of bloodflow on the absorption of theophylline from the jejunum of the rat

N Schurgers, CJ de Blaey - Pharmaceutical research, 1984 - Springer
The influence of the jejunal bloodflow on the absorption of theophylline was investigated.
The bloodflow through a segment under investigation was varied by changing the systemic …